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Job Location: Rockville, MD

Human Resource Generalist

(ID: 2025-1103)

Axle Informatics is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations around the globe. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with premier research organizations and facilities including multiple institutes at the National Institutes of Health (NIH) and other public and private organizations. 

Benefits We Offer:

  • 100% Medical, Dental & Vision Coverage for Employees
  • Educational Benefits for Career Growth
  • Paid Time Off (Including Holidays)
  • Employee Referral Bonus
  • 401K Matching
  • Flexible Spending Accounts:
    • Healthcare (FSA)
    • Parking Reimbursement Account (PRK)
    • Dependent Care Assistant Program (DCAP)
    • Transportation Reimbursement Account (TRN)

Overview: 

 

The Human Resource Generalist will run the daily functions of the Human Resource (HR) department including administering pay, benefits, and leave, and enforcing company policies and practices.

 Duties/Responsibilities:

  • Reviews, tracks, and documents compliance with mandatory and non-mandatory training, continuing education, and work assessments. This may include safety training, anti-harassment training, professional licensure, and aptitude exams and certifications.

  • Conducts or acquires background checks and employee eligibility verifications.

  • Implements new hire orientation and employee recognition programs.

  • Performs routine tasks required to administer and execute human resource programs including but not limited to compensation, benefits, and leave; disciplinary matters; disputes and investigations; performance and talent management; productivity, recognition, and morale; occupational health and safety; and training and development.

  • Handles employment-related inquiries from applicants, employees, and supervisors, referring complex and/or sensitive matters to the appropriate staff.

  • Assist with the payroll cycle utilizing ADP.

  • Conduct research on immigration laws and policies to determine the best pathways for immigration needs.

  • Attends and participates in employee disciplinary meetings, terminations, and investigations.

  • Maintains compliance with federal, state, and local employment laws and regulations, and recommended best practices; reviews policies and practices to maintain compliance.

  • Maintains knowledge of trends, best practices, regulatory changes, and new technologies in human resources, talent management, and employment law.

  • Processes and verifies new hire documentation and ensures accurate employee setup in ADP.

  • Performs routine audits of employee files, work authorization documentation, and I-9 records to ensure full compliance with federal and state laws.

  • Identifies opportunities to automate and streamline HR workflows, improving efficiency and data integrity.

  • Supports HRIS enhancements to improve data quality and usability

  • Demonstrates a strong interest and aptitude in HR technology and process optimization.

  • Performs other duties as assigned.

Required Skills/Abilities:

  • Excellent verbal and written communication skills.

  • Excellent interpersonal, negotiation, and conflict resolution skills.

  • Excellent organizational skills and attention to detail.

  • Excellent time management skills with a proven ability to meet deadlines.

  • Strong analytical and problem-solving skills.

  • Ability to prioritize tasks and to delegate them when appropriate.

  • Ability to act with integrity, professionalism, and confidentiality.

  • Thorough knowledge of employment-related laws and regulations.

  • Proficient with Microsoft Office Suite or related software.

  • Proficiency with or the ability to quickly learn the organizations HRIS and talent management systems.

Education and Experience:

  • Bachelor’s degree in Human Resources, Business Administration, or related field required.

  • At least 1-3 years of human resource management experience preferred.

 

If you are looking to join a team that values innovation, collaboration, and continuous improvement in HR practices, this role offers a chance to shine.

The diversity of Axle’s employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment-based age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate.

Accessibility: If you need an accommodation as part of the employment process, please contact careers@axleinfo.com

Disclaimer: The above is meant to illustrate the general nature of work and level of effort being performed by individual’s assigned to this position or job. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job or responsibilities as needed.

This role has a market-competitive salary with an anticipated base compensation range listed below. Actual salaries will vary depending on a candidate’s experience, qualifications, skills, and location.

Salary Range
$65,000—$70,000 USD

Senior Data Architect

(ID: 2025-1007)

Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations nationally and abroad. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).

 

Benefits We Offer:

  • 100% Medical, Dental & Vision Coverage for Employees
  • Paid Time Off and Paid Holidays
  • 401K match up to 5%
  • Educational Benefits for Career Growth
  • Employee Referral Bonus
  • Flexible Spending Accounts:
    • Healthcare (FSA)
    • Parking Reimbursement Account (PRK)
    • Dependent Care Assistant Program (DCAP)
    • Transportation Reimbursement Account (TRN)

 

Axle is seeking a Senior Data Architect to join our team supporting the National Center for Advancing Translational Sciences (NCATS), located in Rockville, MD.

 

About the Mission

Join the team powering the National COVID Cohort Collaborative (N3C) — now expanding into the National Clinical Cohort Collaborative, the largest harmonized clinical data resource in the United States. N3C integrates diverse, de-identified EHR, claims, registry, and public health data to accelerate discovery and translational research across diseases.

This is not a traditional engineering role. It’s a chance to define how clinical data is represented, harmonized, and made research-ready for thousands of investigators. As a senior architect and informatics leader, you will shape national data standards, ensure semantic interoperability, and help guide the future of data-driven biomedical research.

 

The Opportunity: Your Impact

As a Senior Data Architect, you will lead the design and governance of the data architecture that underpins one of the most ambitious biomedical data resources in existence. You’ll ensure that diverse clinical, administrative, and external datasets are accurately modeled, semantically consistent, and analytically usable across multiple domains.

You will collaborate closely with informaticians, data scientists, and data engineers to ensure data are FAIR (Findable, Accessible, Interoperable, and Reusable) and aligned with national data model initiatives.

 

What You’ll Do

Architect and Evolve the National Clinical Data Model

  • Lead the design and optimization of scalable data models across diverse healthcare domains.
  • Extend and refine OMOP and FHIR vocabularies for evolving data types including genomics, imaging, and environmental data.
  • Define canonical representations of key concepts (diagnoses, labs, medications, encounters, outcomes) to ensure semantic integrity across sources.

     

Advance Data Interoperability and Harmonization

  • Oversee cross-model translation between OMOP, PCORNet, TriNetX, ACT, and FHIR.
  • Govern terminological consistency using SNOMED CT, LOINC, ICD, RxNorm, CPT, and NDC vocabularies.
  • Implement curation pipelines that align heterogeneous data into harmonized, analysis-ready structures.

     

Enable Federated and Privacy-Preserving Research

  • Support linkage of de-identified records across clinical systems, registries, and claims datasets.
  • Guide the implementation of privacy-preserving record linkage (PPRL) and federated learning frameworks.
  • Collaborate with governance teams to ensure compliance with HIPAA, FISMA, and NIH data-sharing policies.

     

Champion Data Quality and Provenance

  • Develop frameworks and dashboards for assessing data completeness, consistency, and validity across contributing sites.
  • Define and track metadata standards to ensure reproducibility and transparency.

     

Provide Strategic Leadership

  • Mentor data scientists and engineers in informatics best practices and semantic data design.
  • Serve as a liaison to standards development organizations (OHDSI, HL7, NCATS CD2H, etc.).
     

What You’ll Bring (Required Qualifications)

  • Master’s or Doctoral degree in Biomedical Informatics, Health Information Science, Computer Science, or a related field.
  • 6+ years of experience in healthcare data architecture, data integration, or clinical informatics.
  • Deep expertise in EHR data, clinical terminologies, and interoperability standards.
    Demonstrated depth of experience working with OMOP, FHIR, or other Common Data Models (CDMs) at scale.
  • Proficiency in SQL and Python along with collaborative experience with engineers on data transformation workflows.
  • Strong understanding of healthcare data sources: EHRs, claims, registries, and observational cohorts.
    Familiarity with data quality frameworks, metadata management, and data governance principles.
  • Proven ability to communicate technical data concepts to scientific and clinical audiences.
     

Preferred Qualifications

  • Experience architecting or managing large-scale, multi-institutional research data repositories.
  • Working knowledge of cloud platforms (AWS, GCP, or Azure) and modern data architectures (e.g., data lakes, knowledge graphs).
  • Experience with workflow orchestration tools like Airflow.
  • Understanding of federated data systems and distributed query infrastructure.
  • Contributions to open-source healthcare informatics projects (e.g., OHDSI, HL7).

     

 

Disclaimer: The above description is meant to illustrate the general nature of work and level of effort being performed by individuals assigned to this position or job description. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job description or responsibilities as needed.

The diversity of Axle’s employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment based on age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate.

Accessibility: If you need an accommodation as part of the employment process please contact: careers@axleinfo.com

This role has a market-competitive salary with an anticipated base compensation range listed below. Actual salaries will vary depending on a candidate’s experience, qualifications, skills, and location.

#IND

Salary Range
$125,000—$150,000 USD

Assistant Director of Education and Capacity-Building

(ID: 2025-0932)

Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations nationally and abroad. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).

 

Axle is seeking a Assistant Director of Education and Capacity-Building to join our vibrant team at the National Institutes of Health (NIH) supporting the National Center for Advancing Translational Sciences (NCATS). This position is remote but does require some travel to Rockville, MD. 

 

Benefits We Offer:

  • 100% Medical, Dental & Vision Coverage for Employees
  • Paid Time Off and Paid Holidays
  • 401K match up to 5%
  • Educational Benefits for Career Growth
  • Employee Referral Bonus
  • Flexible Spending Accounts:
    • Healthcare (FSA)
    • Parking Reimbursement Account (PRK)
    • Dependent Care Assistant Program (DCAP)
    • Transportation Reimbursement Account (TRN)

 

Axle Informatics seeks an experienced, effective Assistant Director of Education and Capacity-Building to lead and manage operations for a portfolio of high-impact education, training, and workforce programs in health data science, artificial intelligence and machine learning (AI/ML), real-world data platforms, and translational research. This role focuses on meeting clients’ needs for pedagogically rich, measurable, scalable, outcomes-focused training programs to strengthen the national workforce.

 

The Assistant Director co-leads an interprofessional team of leaders, educators, instructional designers, writers, and data scientists in a primarily remote environment—fostering clear communication, predictable execution, and measurable impact for government, academic, and industry partners. Working closely with the Director of Education and Capacity-Building, and in partnership with the Training Solutions Architect and Program Manager, the Assistant Director owns day-to-day operations across multiple initiatives—planning and resourcing team workflows, guiding schedules, chairing meetings, overseeing quality and compliance, coordinating cross-functional contributors, and ensuring on-time, high-quality delivery.

 

The ideal candidate is engaging, collaborative, and solutions-oriented, with executive presence and exceptional written and verbal communication. They bring proven experience leading interprofessional teams and managing operations for multisite education, data science, or health-research programs, exercising sound judgment, discretion, and strong stakeholder management to meet scope, schedule, budget, and quality targets. Experience with AI/ML, real-world data, and translational research is preferred, but not required.

 

 

Leadership and Growth

  • Work with the Director of Education and Capacity-Building to oversee and deliver multiple concurrent education and capacity-building programs that advance Axle’s strategic goals and clients’ missions.

  • Support effective relationships with clients, collaborators, and cross-functional partners in government, academia, and industry, ensuring strong client satisfaction and discretion with privileged information.

  • Assist in identifying new growth opportunities and preparing solution outlines and project proposals that align with Axle’s strategy and capacity.

 

Operational and Strategic Management

  • Lead end-to-end operations, including developing operating plans, chairing operations meetings, engaging resources, and monitoring workflows to consistently meet contractual objectives and quality metrics.

  • Collaborate with the Director, Program Manager, and Training Solutions Architect to synthesize data-driven insights that drive decisions, timelines, and contingency plans.

  • Monitor and manage contract execution—ensuring timely delivery, compliance with client policies, audit-ready documentation, and alignment with Axle’s values of integrity, innovation, and partnership.

 

Education Team Development

  • Co-lead an interprofessional team spanning health data science, education, instructional design, technical writing, project management, and communications.

  • Build a positive, engaging, and productive remote work environment that fosters collaboration, cohesion, and continual professional development.

  • Manage the Education Team, including forecasting personnel needs, balancing workloads, chairing team meetings, and performing evaluations.

  • Cultivate multidisciplinary collaborations and a community of learning within and across Axle teams and collaborators, stewarding partnerships that expand scope and impact.

 

Communication

  • Communicate with clarity, authenticity, and professionalism across all levels of the organization.

  • Ensure professional and timely communication, documentation, and reporting for clients, partners, and leadership.

  • Represent Axle’s impact, success, and client-centered culture in meetings, conferences, and working groups focused on education, workforce development, and health data science.

 

Create Impact

  • Produce executive-ready monthly dashboards and briefings summarizing operational performance, reach, and impact, including training outcomes and workforce capacity-building.

  • Prepare and deliver impactful presentations tailored for executive leadership, government clients, multidisciplinary partners, clinical teams, trainees, and professional audiences across the nation.

  • Maintain a living library of content, case studies, personnel bios, slide decks, reports, and one-page scorecards for rapid reuse representing Education and Capacity-Building capabilities and impacts.

 

Required

  • 5+ years of experience directing and managing multicomponent portfolios, preferably in education, training, or workforce programs in science, health, or data-related fields.

  • Master’s degree in business, education, data science, clinical science, informatics, or related discipline.

  • Proven success leading and managing contract operations from proposal to presentation, including overseeing project plans, personnel, workflows, deliverables, and reporting.

  • Experience building and managing relationships across government, academic, and industry sectors.

  • Excellent interprofessional communication and collaboration skills, including discretion with confidential or privileged information.

  • Data- and outcomes-driven decision-making skills, ethical judgment, and a clear understanding of mission-driven strategy, management, and culture.

  • Experience leading multiple complex projects simultaneously using strong organizational, time management, and problem-solving skills.

  • Demonstrated leadership and management experience, including team supervision, workload allocation, and personnel development.

  • Demonstrated Ability to communicate complex ideas clearly and effectively, orally, visually, and in writing, to multidisciplinary audiences.

  • Knowledge of education, data security, and privacy regulations (HIPAA, FERPA, Section 508).

  • Proficiency with Microsoft Workspace (Teams, OneDrive, SharePoint, Outlook) and Google Workspace (Drive, Docs, Sheets).

  • Comfort using online collaboration tools (Slack, Teams, or similar) for remote teams.

  • Strong presentation skills across multiple professions and disciplines.

 

Preferred

  • Doctorate (PhD, EdD, or equivalent) in a relevant field.

  • Experience in healthcare, translational science, real-world data, data science, and AI/ML applications.

  • Experience using generative AI to optimize operational processes.

  • Flexibility and comfort working in dynamic, agile workflows.

  • Experience working with or within government agencies (NIH, NCATS, NASA, PCORI, ARPA-H, NSF, CDC); familiarity with NIH training policies and culture.

  • Strong portfolio of cross-sector projects, including partnerships across industry, government, foundations, and academia.

  • Familiarity with educational and communication technologies such as Articulate, Docebo, Adobe Creative Suite, InDesign, and Camtasia.

  • Familiarity with data science platforms and tools (R, Python, SQL, N3C, Databricks, Notebooks Hub, ATLAS, OHDSI).

  • Experience collaborating with leadership on business and corporate development or strategic growth initiatives.

     

 

Disclaimer: The above description is meant to illustrate the general nature of work and level of effort being performed by individuals assigned to this position or job description. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job description or responsibilities as needed.

The diversity of Axle’s employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment based on age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate.

Accessibility: If you need an accommodation as part of the employment process please contact: careers@axleinfo.com

This role has a market-competitive salary with an anticipated base compensation range listed below. Actual salaries will vary depending on a candidate’s experience, qualifications, skills, and location.

#IND

Salary Range
$130,000—$160,000 USD

Power Apps Lead Architect and Developer

(ID: 2025-0961)

Axle Informatics is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations around the globe. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with premier research organizations and facilities including multiple institutes at the National Institutes of Health (NIH) and other public and private organizations. 

 

Benefits We Offer:

  • 100% Medical, Dental & Vision Coverage for Employees
  • Educational Benefits for Career Growth
  • Paid Time Off (Including Holidays)
  • Employee Referral Bonus
  • 401K Matching
  • Flexible Spending Accounts:
    • Healthcare (FSA)
    • Parking Reimbursement Account (PRK)
    • Dependent Care Assistant Program (DCAP)
    • Transportation Reimbursement Account (TRN)

 

Overview 

The Power Apps Lead Architect and Developer will design, build, and optimize enterprise-grade solutions on Microsoft’s Power Platform, with a focus on scalable architecture, secure integrations, and performance-driven low-code applications. This role requires expert-level understanding of the Power Apps internal runtime model, Dataverse schema design, and PowerFx-based execution patterns. This position requires the ability to work onsite 5 days/week at one of our locations in Rockville, MD, Frederick MD, or Tysons, VA. 

 

 

Key Responsibilities 

  • Architect and implement Power Apps solutions that integrate seamlessly with Microsoft Dataverse, Azure services, and external APIs through standard and custom connectors.
  • Lead design of model-driven and canvas apps, governing solution layering, environment strategy, ALM pipelines, and dependency management across Dev, Test, and Prod environments.
  • Develop and maintain reusable Power Apps components, including PowerApps Component Framework (PCF) controls and custom connectors, packaged and deployed via solution manifests.
  • Oversee low-code application lifecycle management using Azure DevOps and Power Platform Build Tools, including source control of exported app JSON schemas and solution XMLs.
  • Implement PowerFx-based logic, governance policies, and performance instrumentation across Power Platform environments.
  • Collaborate with enterprise security and cloud teams to enforce compliance, data protection, and least-privilege design within Azure AD and Dataverse.
  • Guide developers in understanding internal Power Platform operations — including metadata-driven compilation, connector resolution, PowerFx expression evaluation, and runtime sandboxing within Azure Functions. 

 

Required Skills 

  • Deep expertise in Power Apps (Canvas and Model-Driven), PowerFx, and Dataverse architecture.
  • Proficiency in Power Automate, Power BI integration, and Power Platform Administration.
  • Experience building PCF components, custom connectors, and REST-based integrations.
  • Strong background in Azure Functions, Logic Apps, API Management, and Identity (AAD).
  • Familiarity with JSON, TypeScript, C#, and Power Platform CLI/Build Tools.
  • Proven experience implementing CI/CD pipelines for Power Platform solutions using Azure DevOps.
  • Ability to work onsite at one of our locations 5 days/week in Rockville, MD, Frederick, MD, or Tysons, VA.

 

The diversity of Axle’s employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment-based age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate.

Accessibility: If you need an accommodation as part of the employment process, please contact careers@axleinfo.com

Disclaimer: The above is meant to illustrate the general nature of work and level of effort being performed by individual’s assigned to this position or job. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job or responsibilities as needed.

This role has a market-competitive salary with an anticipated base compensation range listed below. Actual salaries will vary depending on a candidate’s experience, qualifications, skills, and location.

#IND

Salary Range
$120,000—$130,000 USD

Senior Full Stack Developer

(ID: 2025-0876)

Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations nationally and abroad. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).

 

Benefits We Offer:

  • 100% Medical, Dental & Vision Coverage for Employees
  • Paid Time Off and Paid Holidays
  • 401K match up to 5%
  • Educational Benefits for Career Growth
  • Employee Referral Bonus
  • Flexible Spending Accounts:
    • Healthcare (FSA)
    • Parking Reimbursement Account (PRK)
    • Dependent Care Assistant Program (DCAP)
    • Transportation Reimbursement Account (TRN)

 

Axle is seeking a Senior Full Stack Developer to join our vibrant team at the National Institutes of Health (NIH) supporting the National Center for Advancing Translational Sciences (NCATS) located in Rockville, MD.

 

Responsibilities

  • Build scalable, reliable, and flexible applications in TypeScript using NodeJS and Angular 19+

  • Design, implement, and/or use RESTful web services

  • Implement modern and responsive UI for the web and variety of devices

  • Participate in agile software development, prototyping, testing, and code reviews with a small team of developers

  • Write robust unit and end-to-end tests

 

Basic Qualifications

  • Experience with data visualization technologies (i.e., D3.js)

  • Bachelor’s Degree in Computer Science, Data Science, Bioinformatics or other related field (years of work experience will be considered in lieu of degree)

  • 3+ years experience working with TypeScript/JavaScript

  • 3+ years experience as a full-stack developer

  • Experience with the following:

    • Node.js

    • Angular 19+

    • SQL databases (PostgreSQL)

    • Containers and container orchestration tools (Docker, Kubernetes)

    • DevOps tools (Jenkins, GitHub Actions)

  • Familiarity with VCS such as Git

  • Experience with unit and end-to-end testing frameworks

  • Experience with using and leveraging GenAI technologies (i.e., CursorAI, Cline, Windsurf)

 

Relevant Skills

  • Familiarity with biomedical research data

  • Critical thinking, problem solving, and attention to detail

  • Clear, concise communication

  • Technical writing ability

  • Familiarity working in an Agile environment

  • Attention to detail when building visually appealing and intuitive UI

 

Disclaimer: The above description is meant to illustrate the general nature of work and level of effort being performed by individuals assigned to this position or job description. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job description or responsibilities as needed.

The diversity of Axle’s employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment based on age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate.

Accessibility: If you need an accommodation as part of the employment process please contact: careers@axleinfo.com

This role has a market-competitive salary with an anticipated base compensation range listed below. Actual salaries will vary depending on a candidate’s experience, qualifications, skills, and location.

#IND

Salary Range
$140,000—$160,000 USD

Senior Healthcare Data Engineer

(ID: 2025-0941)

Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations nationally and abroad. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).

 

Axle is seeking a Senior Healthcare Data Engineer to join our vibrant team at the National Institutes of Health (NIH) supporting the National Center for Advancing Translation Sciences (NCATS) located in Rockville, MD.

 

Benefits We Offer:

  • 100% Medical, Dental & Vision Coverage for Employees
  • Paid Time Off and Paid Holidays
  • 401K match up to 5%
  • Educational Benefits for Career Growth
  • Employee Referral Bonus
  • Flexible Spending Accounts:
    • Healthcare (FSA)
    • Parking Reimbursement Account (PRK)
    • Dependent Care Assistant Program (DCAP)
    • Transportation Reimbursement Account (TRN)

 

 

About the Mission:

Join the team at the forefront of revolutionizing medical research in the United States. We are building and maintaining the foundational infrastructure of the National Clinical Cohort Collaborative (N3C), the nation’s largest and most significant public repository of harmonized electronic health record (EHR) data. What began as a critical response to the pandemic has evolved into a multi-disease, terabyte-scale resource that empowers researchers to make discoveries faster than ever before.

This isn’t just another data engineering job. This is a chance to leave your mark on a national-scale platform, solve complex data challenges that directly impact public health, and work with a passionate team dedicated to smarter science and better treatments for all.

 

The Opportunity: Your Impact

We are looking for a visionary Senior Healthcare Data Engineer to be a lead architect of our data ingestion and harmonization ecosystem. You will be instrumental in N3C’s next evolutionary step: the transition to a scalable, secure, and flexible “Dynamic Workspaces” model. You won’t just be maintaining pipelines; you will be re-architecting, modernizing, and scaling the systems that ingest and harmonize a diverse torrent of data. From EHRs and CMS claims to cancer registries and geospatial data, you will be making it research-ready for thousands of scientists.

If you are a builder who thrives on complex challenges and wants your work to have a tangible, lasting impact on science and medicine, we want to talk to you.

 

What You’ll Do:

  • Architect and Modernize National-Scale Data Pipelines: Design, develop, and optimize robust, disease-agnostic data acquisition and ingestion pipelines built to handle the complexity and scale of N3C.
  • Master Data Integration and Harmonization: Tackle the complex challenge of harmonizing heterogeneous clinical data from countless sources. You will maintain and enhance the OMOP harmonization pipeline, improve interoperability between common data models (e.g., OMOP, PCORNet, FHIR), and ensure consistency for critical data like medications and lab values.
  • Build the Future with Dynamic Workspaces: Be a key technical player in developing the infrastructure for N3C’s new Dynamic Workspaces. You will help build the systems that provision secure, project-specific analytical environments, giving researchers access to the specific data they need while providing institutions granular control.
  • Champion Data Quality and Governance: Develop and implement sophisticated data quality frameworks, creating dashboards and feedback loops to ensure our data partners and researchers have transparent insight into data completeness, consistency, and quality.
  • Innovate with Advanced Technologies: Integrate critical new data sources, including national mortality data and CMS. You will link datasets and help build the processes for integrating novel data types like geospatial and environmental data.
  • Collaborate and Lead: Work alongside a world-class team of scientists, project managers, and engineers to translate scientific needs into technical solutions. You will provide technical leadership and mentorship, driving best practices in an agile, mission-focused environment.

 

What You’ll Bring (Required Qualifications):

  • A deep passion for using technology to solve meaningful problems in healthcare and medical research.
  • Bachelor’s or Master’s degree in Computer Science, Data Engineering, Bioinformatics, or a related field, with 8+ years of hands-on experience in data engineering (or 5+ years with a Master’s).
  • Expert-level proficiency in Python and SQL, with a proven track record of building and maintaining complex, large-scale data pipelines and ETL processes.
  • Significant experience with healthcare data is essential. You must have deep, practical knowledge of common data models (CDMs), particularly OMOP and/or FHIR, and experience with clinical terminologies (e.g., ICD, SNOMED, RxNorm).
  • Strong experience with big data technologies (e.g., Apache Spark, Hadoop) and containerization using Docker for creating reproducible and scalable workflows.
  • Proficiency with version control (Git) and CI/CD practices for data infrastructure.
  • An architectural mindset with the ability to design for scalability, reliability, and security.

 

What Sets You Apart (Preferred Qualifications):

  • Experience designing and deploying data solutions on cloud platforms (AWS, GCP, Azure).
  • Proficiency with modern workflow management systems (e.g., Nextflow, Snakemake, Airflow).
  • Experience with privacy-preserving record linkage (PPRL) techniques and the challenges of working with de-identified patient data.
  • Familiarity with federated data systems and architectures.
  • Experience working in a regulated data environment (e.g., FISMA, HIPAA).

 

 

Disclaimer: The above description is meant to illustrate the general nature of work and level of effort being performed by individuals assigned to this position or job description. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job description or responsibilities as needed.

The diversity of Axle’s employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment based on age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate.

Accessibility: If you need an accommodation as part of the employment process please contact: careers@axleinfo.com

This role has a market-competitive salary with an anticipated base compensation range listed below. Actual salaries will vary depending on a candidate’s experience, qualifications, skills, and location.

#IND

Salary Range
$150,000—$190,000 USD

IT Program Manager

(ID: 2025-0917)

Axle Informatics is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations around the globe. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with premier research organizations and facilities including multiple institutes at the National Institutes of Health (NIH) and other public and private organizations. 

 

Axle is currently hiring a dynamic, driven, and solution oriented IT Program Manager in Rockville, MD to lead the integration and management of authorization solutions.

 

Benefits We Offer:

  • 100% Medical, Dental & Vision Coverage for Employees
  • Educational Benefits for Career Growth
  • Paid Time Off (Including Holidays)
  • Employee Referral Bonus
  • 401K Matching
  • Flexible Spending Accounts:
    • Healthcare (FSA)
    • Parking Reimbursement Account (PRK)
    • Dependent Care Assistant Program (DCAP)
    • Transportation Reimbursement Account (TRN)

 

Overview

We are seeking a skilled IT Program Manager to lead complex programs, ensuring on-time delivery, contract compliance, and strong client relationships. This role combines program leadership with expertise in federal contracting and authorization solutions to drive mission success. 

 

Responsibilities

  • Manage the full lifecycle of government-sponsored programs, ensuring on-time, within-budget delivery and adherence to scope and deliverables.
  • Lead the integration and management of authorization solutions, with a focus on overseeing Software-as-a-Service system delivery and support for secure, compliant access across users, systems, and datasets.
  • Develop project plans, track milestones, and coordinate cross-functional teams to deliver scientific, technical, and administrative support services.
  • Monitor compliance with federal contract requirements, policies, and reporting standards.
  • Serve as the primary point of contact for government clients, building and maintaining strong client relationships by anticipating needs, addressing concerns, and providing strategic guidance.
  • Translate client objectives into actionable plans and ensure solutions align with mission outcomes.
  • Support growth by identifying new opportunities within existing contracts and accounts.
  • Partner with technical staff to evaluate, recommend, and implement authorization and identity management frameworks, including software enhancements and related access control systems.
  • Ensure adherence to government security and privacy requirements, supporting audits, compliance activities, and reporting specific to authorization platforms.
  • Prepare progress reports, briefings, and presentations for federal sponsors and internal leadership.
  • Track program performance metrics and recommend improvements for efficiency and effectiveness.
  • Manage budgets, staffing plans, and subcontractor performance as needed.

 

Qualifications

  • Strong knowledge of authorization and identity management solutions, including demonstrated experience managing government access control frameworks.
  • 5+ years of program management or account management experience with federal government clients.
  • Demonstrated success leading multi-disciplinary teams in a government contracting environment.
  • Experience with NIH institutes strongly preferred.
  • Proven track record in federal contract management and client relationship management.
  • Excellent communication, negotiation, and stakeholder management skills.
  • Bachelor’s degree in business administration, public administration, computer science, or related field.
  • PMP, CSM, or similar certifications desirable.

 

The diversity of Axle’s employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment-based age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate.

Accessibility: If you need an accommodation as part of the employment process, please contact careers@axleinfo.com

Disclaimer: The above is meant to illustrate the general nature of work and level of effort being performed by individual’s assigned to this position or job. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job or responsibilities as needed.

This role has a market-competitive salary with an anticipated base compensation range listed below. Actual salaries will vary depending on a candidate’s experience, qualifications, skills, and location.

#IND

Salary Range
$140,000—$160,000 USD

IT Operations Technical Lead

(ID: 2025-0916)

Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations nationally and abroad. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).

 

Axle is seeking a IT Operations Technical Lead to join our vibrant team at the National Institutes of Health (NIH) supporting the National Center for Advancing Translation Sciences (NCATS) located in Rockville, MD.

 

Benefits We Offer:

  • 100% Medical, Dental & Vision Coverage for Employees
  • Paid Time Off and Paid Holidays
  • 401K match up to 5%
  • Educational Benefits for Career Growth
  • Employee Referral Bonus
  • Flexible Spending Accounts:
    • Healthcare (FSA)
    • Parking Reimbursement Account (PRK)
    • Dependent Care Assistant Program (DCAP)
    • Transportation Reimbursement Account (TRN)

 

Overview

In this role, you will have the opportunity to design, implement, secure and enhance our on-prem and cloud infrastructure and systems. Your experience with IT Operations and Cloud Application support will be used to create roadmaps for operational efficiency, and maintenance. Working alongside other operations teams and development engineering teams, you will collaborate with colleagues and client team members supporting network and architecture assessment, Authorization to Operate (ATO), threat modeling, vulnerability assessment, and security operations. 

 

Responsibilities

  • Oversee On-Prem & Cloud daily technical operations
  • Apply appropriate security measures to safeguard government systems by implementing industry-standard best practices adequately and NIH-mandated
  • Assume a technical lead role in the administration and management of infrastructure solutions that are deployed on-prem and in all major cloud service provides in accordance with Security Guidelines
  • Installing, configuring, maintaining, and supporting applications and servers
  • Performing operating system and software installation, testing, patching and upgrades
  • Monitoring the Heath of internal environment and connections
  • Research new technologies that are applicable to current projects and make recommendations to improve performance, optimize operations, and reduce costs
  • Architecting and leading the migration of legacy On-Prem solution migrations to Cloud Environments with High Performance and reliability
  • Assist in managing technology in projects and providing technical guidance or solutions for task completion
  • Participate in technical discussions or review as a technical consultant for solutions feasibility studies (technical alternatives, best packages, supporting architecture best practices, technical risks, breakdown into components, estimations)
  • Continuously collaborate with the Software Development teams in addressing Operational technical debt
  • Conduct periodic security checks/audits in to ensure Environment compliance with Government guidance and directives
  • Develop and guide team members in enhancing their technical capabilities and increasing productivity

 

Qualifications

  • 8+ years of IT Operations experience
  • 5+ years of supporting Cloud Services (AWS, Azure, GCP)
  • Bachelor’s degree in computer science, engineering, or similar field
  • Experience working with and securing cloud services such as AWS EC2, EKS, GuardDuty, ELB, ECS, IAM, S3, RDS, CloudTrail, CloudFront, and AWS Config
  • Experience assessing the security of the cloud and Kubernetes environments
  • Knowledge of ITSM tools such as ServiceNow or Remedy
  • Demonstrated knowledge preparing guidance related to Cybersecurity best practices within the framework of NIST publications, ISO 2700 Series, CIS, OWASP, RMF, and the various control families within
  • Experience configuring and maintaining monitoring tools, SIEM’s, IDSs, IPS, etc.
  • Experience with a programming or scripting language such as Ruby, Go, or Python
  • Knowledgeable on zero trust architecture concepts such as Google BeyondCorp

 

Disclaimer: The above description is meant to illustrate the general nature of work and level of effort being performed by individuals assigned to this position or job description. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job description or responsibilities as needed.

The diversity of Axle’s employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment based on age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate.

Accessibility: If you need an accommodation as part of the employment process please contact: careers@axleinfo.com

This role has a market-competitive salary with an anticipated base compensation range listed below. Actual salaries will vary depending on a candidate’s experience, qualifications, skills, and location.

#IND

Salary Range
$140,000—$160,000 USD

High-Performance Computing (HPC) Systems Engineer

(ID: 2025-0683)

Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations nationally and abroad. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).

 

Axle is seeking a High-Performance Computing (HPC) Systems Engineer to join our vibrant team at the National Institutes of Health (NIH) supporting the The National Center for Advancing Translational Sciences (NCATS) located in Rockville, MD.

 

Benefits We Offer:

  • 100% Medical, Dental & Vision Coverage for Employees
  • Paid Time Off and Paid Holidays
  • 401K match up to 5%
  • Educational Benefits for Career Growth
  • Employee Referral Bonus
  • Flexible Spending Accounts:
    • Healthcare (FSA)
    • Parking Reimbursement Account (PRK)
    • Dependent Care Assistant Program (DCAP)
    • Transportation Reimbursement Account (TRN)

 

Overview: 

The High-Performance Computing (HPC) Systems Engineer will support the Scientific Computing and Informatics (SCI) team at The National Center for Advancing Translational Sciences (NCATS). This role will focus on the design, optimization, security, and maintenance of HPC and cloud-based infrastructures that enable cutting-edge biomedical research through scalable, secure, and high-performing computing environments. 

 

 

Responsibilities: 

  • Design, configure, and maintain scalable HPC clusters for optimal performance. 

  • Support documentation and ATO (Authority to Operate) processes. 

  • Ensure infrastructure design compliance with federal security standards and best practices. 

  • Implement monitoring tools such as XDMoD for transparency and user reporting. 

  • Integrate platforms such as JupyterHub and job schedulers (e.g., Slurm) for improved interactivity. 

  • Develop and manage AWS-based infrastructure using Terraform, Packer, and Ansible. 

  • Automate deployment workflows to streamline provisioning, updates, and scaling. 

  • Manage systems involved in AWS Secure Cloud Bridging (SCB) and STRIDES initiatives. 

  • Implement CIS benchmark-aligned system hardening using OpenSCAP. 

  • Administer optimized compute images (CPU/GPU) for scientific workflows. 

  • Leverage tools such as OpenHPC, Warewulf, and Ansible for environment management. 

  • Lead and coordinate quarterly patch cycles. 

  • Partner with researchers and external stakeholders on critical projects. 

  • Facilitate solution transitions to other NIH centers and collaborators. 

  • Contribute to publications and team objectives through deep technical engagement. 

 

 

Qualifications: 

  • Federal ATO processes experience required 

  • HPC architecture and performance optimization is required 

  • Scientific software development and deployment 

  • High-speed network and parallel file system architecture 

  • Troubleshooting, diagnostics, and technical support 

  • Strong communication and multitasking skills 

  • Programming & Scripting:  

  • Languages – Pascal, BASIC, Delphi, Visual Basic, C, C++ 

  • Scripting – Bash, Perl, Python, Ruby, PEAR, Tcl 

  • Systems & Network Administration:  

  • Linux – RHEL/CentOS, SUSE, Debian, Ubuntu 

  • Windows – 95–10; NT–Server 2016 

  • Networking – Active Directory, TCP/IP v4/v6, DHCP, DNS, WINS 

  • Legacy – NOVELL 3.1–5, VPN, Citrix, Terminal Services 

  • Monitoring & Management Tools:  

  • Nagios, Ganglia, HP BAC, Precise i3 

  • SGI SMC, HP PCM, Bright Cluster Manager (incl. Data Analytics) 

  • Infrastructure & Automation:  

  • Puppet, Cobbler, Ansible, Chef 

  • Red Hat Satellite, Kickstart, RPM optimization 

  • File Systems & Archiving:  

  • Panasas (DirectFlow/panfs), DDN (GPFS), SGI DMF, StorHouse/RFS (Filetek) 

  • HPC Tools & Job Scheduling:  

  • MOAB/MAUI, Torque, PBS Pro, Windows HPC Scheduler 

  • Visualization & Remote Access:  

  • Nice DCV, EnginFrame, VNC, OpenText Exceed OnDemand, Web Remote Desktop 

  • Containerization & GPU:  

  • Docker, Kubernetes, Kubeflow, NVIDIA DGX-1 GPU systems 

  • Databases:  

  • SQL Server (2000–2008), MySQL, Zope 

  • High-Speed Networking:  

  • Infiniband, Mellanox, OFED, Voltaire, Force10 

  • Proven experience in: 

  • HPC architecture and performance tuning 

  • Cybersecurity in HPC/cloud environments 

  • Infrastructure as Code (AWS, Terraform, Ansible, Packer) 

  • Supporting scientific workflows in research environments 

 

 

 

Disclaimer: The above description is meant to illustrate the general nature of work and level of effort being performed by individuals assigned to this position or job description. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job description or responsibilities as needed.

The diversity of Axle’s employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment based on age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate.

Accessibility: If you need an accommodation as part of the employment process please contact: careers@axleinfo.com

This role has a market-competitive salary with an anticipated base compensation range listed below. Actual salaries will vary depending on a candidate’s experience, qualifications, skills, and location.

#INDPSD

Salary Range
$150,000—$160,000 USD

Business Development Manager, Staffing Solutions

(ID: 2025-0614)

Axle Informatics is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations around the globe. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with premier research organizations and facilities including multiple institutes at the National Institutes of Health (NIH) and other public and private organizations. 

 

Axle is seeking a dynamic, results-driven Business Development Manager, Staffing Solutions with deep expertise in the healthcare, research, and technology domains, spanning both federal government contracting and commercial industry. This role is designed for a top producer and accomplished sales professional with an existing portfolio of clients and a proven track record of generating an immediate revenue impact. 

 

Benefits We Offer:

  • 100% Medical, Dental & Vision Coverage for Employees
  • Educational Benefits for Career Growth
  • Paid Time Off (Including Holidays)
  • Employee Referral Bonus
  • 401K Matching
  • Flexible Spending Accounts:
    • Healthcare (FSA)
    • Parking Reimbursement Account (PRK)
    • Dependent Care Assistant Program (DCAP)
    • Transportation Reimbursement Account (TRN)

 

 Overview: 
The Business Development Manager, Staffing Solutions accelerates company growth by developing new business, cultivating client partnerships, and executing staffing strategies that win competitive bids, maximize margins, and expand market share, measured by clear performance and profitability targets. This position offers an exceptional incentive plan aligned with individual and company performance. 

 

Responsibilities: 

  • Leverage long-standing client relationships and industry connections to achieve business growth and expand market presence in healthcare, research, and technology sectors. 

  • Develop and execute aggressive sales strategies to capture market share in both federal contracting and commercial enterprise accounts. 

  • Negotiate profitable rates, contract terms, and SOW agreements to maximize gross margins. 

  • Act as a trusted advisor to Program Managers, procurement officers, and commercial decision-makers, providing solutions that advance their goals and priorities. 

  • Conduct regular business reviews with key accounts to identify new project pipelines and staffing needs. 

  • Build multi-level relationships to secure sole-source and long-term contract awards. 

  • Collaborate with recruitment and delivery for high-demand, hard-to-fill roles in healthcare, biomedical research, IT, data analytics, cybersecurity, and emerging technologies. 

  • Ensure rapid, quality-driven candidate submittals that meet skill requirements. 

  • Track and report on sales pipeline, contract wins, and gross margin by sector. 

  • Forecast revenue growth by account and domain, ensuring alignment with company P&L goals. 

 

Qualifications: 

  • Bachelor’s degree in business, HR, or related field (Master’s a plus). 

  • Proven track record of revenue generation in staffing or workforce solutions for healthcare, research, and technology sectors. 

  • Existing portfolio of client relationships in the private and public sectors. 

  • Experience building influential relationships and leveraging strategic networking to open doors and drive business growth. 

  • Understanding of procurement processes, capture management, and proposal development. 

  • Strong negotiation skills and proven ability to close high-value deals. 

  • Revenue-first, entrepreneurial mindset. 

  • Strategic leadership and operational excellence. 

 

If you are a proven business generator with deep industry expertise, a relentless drive for revenue growth, and the ability to turn opportunities into long-term partnerships, we want you on our team! 

The diversity of Axle’s employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment-based age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate.

Accessibility: If you need an accommodation as part of the employment process, please contact careers@axleinfo.com

Disclaimer: The above is meant to illustrate the general nature of work and level of effort being performed by individual’s assigned to this position or job. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job or responsibilities as needed.

This role has a market-competitive salary with an anticipated base compensation range listed below. Actual salaries will vary depending on a candidate’s experience, qualifications, skills, and location.

#IND

Salary Range
$70,000—$95,000 USD