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Job Location: Rockville, MD

Patent Paralegal

(ID: 2025-0842)

Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations around the globe. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).

Benefits:

  • 100% Medical, Dental & Vision Coverage for Employees
  • Paid Time Off (Including Holidays)
  • Employee Referral Bonus
  • 401K Match
  • Tuition reimbursement and professional development opportunities
  • Flexible Spending Accounts:
    • Healthcare (FSA)
    • Parking Reimbursement Account (PRK)
    • Dependent Care Assistant Program (DCAP)
    • Transportation Reimbursement Account (TRN)

Overview

Axle is looking to add a driven, flexible, organized, and meticulous Patent Paralegal to our dynamic team. The Contractor(s) shall provide services in support of the overall functions of the Technology Transfer and Intellectual Property Office (TTIPO), National Institute of Allergy and Infectious Diseases (NIAID).

 

Technical Requirements:

 

  • Manage all aspects of patent-related work in support of the TTIPO Technology Transfer and Patent Specialists (TTPS) including:
    • Prepare and route invention/patent filing recommendation packages for review,
    • Enter and analyze data, perform data quality checks, review and attach information relating to patent-filing, patent annuities, procurement of patent legal services, patent workflow.
  • Stay abreast of changes in the US and foreign patent laws and policies that have implications for NIAID and CDC patent portfolios and help implement necessary process and database adjustments to comply with appropriate changes.
  • Review and monitor patent annuity and maintenance fee payment deadlines and data in internal and external databases, ensure contracted annuity management service makes payments in accordance with patent filing recommendations and decisions made by NIAID and CDC and prepare upcoming patent annuity reports for review by TTPS periodically and as needed.
  • Support effective management of NIAID and CDC intellectual property and of the Patent and Legal Services (“PLS”) task orders. Analyze patent budget, expenses and project foreseeable costs associated with pursuing domestic and/or foreign patent protection for NIAID and CDC inventions.
  • Generate reports to identify upcoming patent application filing deadlines, to analyze and determine a patent filing strategy in advance of deadlines, and to track patent expenditures on a monthly and quarterly basis.
  • Identify estimates from the patent law firms for TTIPO staff review; analyze estimated costs for NIAID and CDC to project and plan for funding of patent prosecution activities in the coming year; collect information under PLS task orders to support the COR’s planning activities.

  • Generate and analyze monthly and quarterly PLS Contractors Estimate Reports to ensure accuracy of invoicing and allow early billing discrepancies identification and resolution.

    Assist in the identification of remaining funds for timely obligations.

  • Provide Quarterly Reports on NIAID/CDC patent expenses with remaining funds to TTPS; review reports received from PLS Contractors related to activities under the PLS task orders; identify discrepancies between PLS reports and internal databases; and prepare communications regarding such reports.
  • Assist with review and management of third-party patent filings where NIAID or CDC staff are named as inventors; prepare and forward formal patent documents to third party as appropriate.
  • Perform all actions to support and implement NIAID and CDC authorizations to discontinue patent prosecution.
  • Provide support for the administration of PLS contract; verify and review incoming law firm billing and invoicing documents for accuracy and formal requirements.
  • Coordinate reconsideration of and refunds for rejected invoices by PLS Contractors.
  • Monitors PLS Contractors’ invoice submission process for accuracy and timeliness.
  • Become provisioned for invoice reviewer role in the NIH Business System (NBS) and perform this function for PLS invoices under the direction of NIH contracting officers and TTIPO Contracting Officers Representative.
  • Ensure PLS invoice payment to vendors is recorded in ETT in a timely manner based on information in NBS to enable patent prosecution reimbursement from licensees of NIAID patent portfolio.
  • Communicate with law firms regarding filing confirmations, patent data, formal document requirements.
  • Generate new patent records in the database based on TTIPO patent filing decisions.
  • Docket Office Actions from the USPTO and Patent Offices worldwide and responses filed by law firms for patent prosecution matters; discern actionable items for TTIPO staff, as appropriate.
  • Manage all aspects of license agreement-related work in support of the TTIPO Technology Transfer and Patent Specialist (TTPS) including license application review, database entries, licensing-related documentation review, maintenance and retention, and licensing workflow navigation.
  • Review, analyze and maintain licensing agreements and forecast future royalty income for NIAID and CDC; create executive summaries of license agreements; communicate with licensees under the direction of TTPS.
  • Route negotiated and finalized agreements for signature by NIH and applicants; close out and process executed agreements in appropriate databases.
  • Generate reports relating to incurred and unreimbursed patent expenses for patent portfolios being licensed under agreements.
  • Routinely assist with license royalty review, analysis, reporting and distribution.
  • Provide assistance with license monitoring and enforcement activities for the NIAID and CDC portfolios.
  • Enter data into and analyze data in databases, perform data quality checks, maintain database integrity for all actions relating to: patents, employee invention reports (EIR), patent maintenance and annuities, agreements and post-execution agreement compliance documentation. Data could broadly pertain to Licenses, Confidentiality Disclosure Agreements (CDAs), Material Transfer Agreements (MTAs), Conditional Gift Fund Agreements (CGFs), Cooperative Research and Development Agreements (CRADAs), Sales and Progress reports, etc, and data related to the administration of the patent legal services contract.
  • Participate in record retention policy implementation in databases and in physical records; timely remove records according to NARA approved record retention schedules.
  • Generate docket reports and help assure that upcoming deadlines are communicated within the office.
  • Make recommendations to TTIPO Director and other staff members to develop an acceptable plan for technical and administrative matters, including identification of work to be done, the scope to the project, and deadlines for completion, and proceeding independently.
  • Coordinate with TTIPO staff on assignments with broadly defined goals or mission to be accomplished and support with implementation as required.
  • Assist with preparation for and during TEAC and pre-TEAC meetings, and with post- TEAC proceedings
  • Assist with advertising and marketing efforts; prepare and submit materials for publications in Federal Register, LinkedIn, and other publications; assist in the administration of technology transfer agreements as necessary including managing communications with external organizations and NIAID divisions in regard to the biological materials and establishing simple agreements.
  • Originate, review and draft cover letters and memos, and various other documents.
  • Prepare training and standard operating procedure documents as needed to support TTIPO operations and use of databases.
  • Provide accurate verbal and written responses to inquiries regarding the status of technology transfer agreements.
  • Coordinate with staff members to complete special projects including preparation of educational and marketing materials.
  • Generate miscellaneous patent and licensing reports, as needed.
  • Provide Notary Public services for Technology Transfer documents.

 

Specific Qualifications:

 

  • At least 3 years of patent paralegal experience in a law firm required.
  • The education, skills and relevant years of experience required for each support position are consistent with those identified as the minimum requirements for the labor categories specified in
    the contract.

The diversity of Axle’s employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment-based age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate.

Accessibility: If you need an accommodation as part of the employment process please contact: careers@axleinfo.com

Disclaimer: The above description is meant to illustrate the general nature of work and level of effort being performed by individual’s assigned to this position or job description. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job description or responsibilities as needed.

This role has a market-competitive salary with an anticipated base compensation range listed below. Actual salaries will vary depending on a candidate’s experience, qualifications, skills, and location.

#INDPSD

Salary Range
$95,000—$110,000 USD

Process Analyst

(ID: 2025-0797)

Axle Informatics is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations around the globe. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with premier research organizations and facilities including multiple institutes at the National Institutes of Health (NIH) and other public and private organizations. 

 

Axle is currently hiring a detail oriented and analytical Process Analyst to support and enhance operations across our Administrative Delivery Unit. This position requires the ability to work in our Rockville, MD office 5 days/week. 

 

Benefits We Offer:

  • 100% Medical, Dental & Vision Coverage for Employees
  • Educational Benefits for Career Growth
  • Paid Time Off (Including Holidays)
  • Employee Referral Bonus
  • 401K Matching
  • Flexible Spending Accounts:
    • Healthcare (FSA)
    • Parking Reimbursement Account (PRK)
    • Dependent Care Assistant Program (DCAP)
    • Transportation Reimbursement Account (TRN)

 

Overview:

The Administrative Delivery Unit supports other organizational delivery units in the areas of contract administration, program service support and budget analysis/accounting.  This Process Analyst role is ideal for a professional who thrives on improving workflows, ensuring compliance, and driving operational efficiency through data-driven insights and process optimization. 

 

 

Responsibilities:

  • Play a central role in identifying, documenting, and enhancing workflows throughout the Administrative Delivery Unit. 
  • Use data-driven insights to assess current processes, partner with stakeholders to gather feedback, and lead initiatives that streamline operations and boost overall efficiency.
  • Monitor and evaluate the impact of process changes, recommending further improvements as needed.
  • Drive automation and workflow integration by developing and implementing custom solutions using Power Apps. These applications will streamline routine tasks, enhance data collection, and enable seamless connectivity across systems, ultimately empowering staff with more efficient tools.
  • Leverage AI-driven solutions to uncover actionable trends within large datasets and provide stakeholders with real-time insights. Stay informed on emerging AI technologies and recommend innovative tools and strategies that further optimize operations and support data-driven decision-making throughout the unit. 

 

Qualifications:

  • 1-3 Years of professional experience
  • Ability to work as part of an integrated team
  • Technological Acumen:
    • Demonstrates an openness to learning new digital tools, platforms, and emerging technologies, with a willingness to explore automation and system integration as needed
    • Demonstrates the ability to quickly learn and adapt to new software and applications, ensuring operational excellence and forward-thinking solutions in a dynamic environment
  • Strong analytical thinking:
    • Capable of evaluating information, identifying patterns, and proposing practical solutions to challenges
  • Adaptability:
    • Comfortable with change and able to adjust quickly to new processes, technologies, and environments
  • Bachelor’s Degree

 

Preferred Skills:

  • Familiarity with Microsoft Power Apps and AI-driven tools is highly valued, but not necessary, enabling efficient automation, improved data analysis, and intuitive workflow solutions
  • Comfort with adopting new technologies and leveraging modern digital platforms to support innovation across administrative functions is a plus

The diversity of Axle’s employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment-based age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate.

Accessibility: If you need an accommodation as part of the employment process, please contact careers@axleinfo.com

Disclaimer: The above is meant to illustrate the general nature of work and level of effort being performed by individual’s assigned to this position or job. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job or responsibilities as needed.

This role has a market-competitive salary with an anticipated base compensation range listed below. Actual salaries will vary depending on a candidate’s experience, qualifications, skills, and location.

#IND

Salary Range
$60,000—$65,000 USD

Pharmacoepidemiologist, Causal Inference

(ID: 2025-0803)

Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations nationally and abroad. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).

 

Axle is seeking a talented Pharmacoepidemiologist to join our team to support projects at the NIH’s National Center for Advancing Translational Sciences (NCATS). In this role, you will collaborate with clinical and data scientists, methodologists, and software engineers to develop and execute exemplar causal inference studies. You will work as a subject matter expert to create a real-world evidence (RWE) methods decision tree; support master protocol development; and support development of gold-standard guides and methodologies for conducting best practices causal inference research. You will: design, execute, and analyze studies using the National Clinical Cohort Collaborative (N3C) data; review and recommend strategies for selecting study designs to answer causal inference questions; help establish, and implement appropriate analytic value sets. 

 

Benefits We Offer:

  • 100% Medical, Dental & Vision Coverage for Employees
  • Paid Time Off and Paid Holidays
  • 401K match up to 5%
  • Educational Benefits for Career Growth
  • Employee Referral Bonus
  • Flexible Spending Accounts:
    • Healthcare (FSA)
    • Parking Reimbursement Account (PRK)
    • Dependent Care Assistant Program (DCAP)
    • Transportation Reimbursement Account (TRN)

 

 

Overview:

The ideal candidate for the Pharmacoepidemiologist position is a highly skilled professional with a Ph.D. in Pharmacoepidemiology, Epidemiology, Biostatistics, Causal Inference or related field. This person has experience with electronic health record and/or claims data and a strong understanding of observational study principles including: missing data handling methods; temporal research questions (cross-sectional, longitudinal); causal contrast of interest (e.g., intent-to-treat, per-protocol); effect measure of interest (e.g., risk ratio, hazard ratio); and estimands (e.g., average treatment effect, average treatment effect in the treated) of interest. Your research experience includes one or more of the following: target trial emulation, sequential trial analysis, marginal structural models, longitudinal matching, G methods, or equivalent causal inference methods, realized in multiple primary-author publications. Fluency with coding languages and tools is expected (i.e. SQL, Python, and R). 

 

Responsibilities: 

  • Serve as SME for RWE causal inference studies. 

  • Design and execute studies with N3C EHR data considering the following: extent of missing data; missing data handling methods; temporal component of research studies (i.e. cross-sectional, longitudinal); the causal contrast of interest (e.g., intent-to-treat, per-protocol); the effect measure of interest (e.g., risk ratio, hazard ratio); and estimand (e.g., average treatment effect, average treatment effect in the treated) of interest. 

  • Review and recommend strategies for selecting individuals in clinical cohorts. 

  • Ensure the highest data quality and minimization of bias. 

  • Use tools and languages such as Python, R, SQL, and Spark. 

  • Help establish and implement appropriate analytic value sets. 

  • Collaboratively produce extensive documentation (i.e. through training material, research protocols, open data sources such as repositories and/or methodological and research papers). 

  • Work closely with data science and software developer teams to articulate technical methods and implement decision tool strategies. 

  • Extract and transform clinical data from clinical trial and observational studies. 

  • Participate in project meetings, provide updates on progress, challenges, and mitigation strategies. 

  • Actively engage in key relevant meetings and keep abreast of emerging best practices and methods. 

 

Required Qualifications:

  • Ph.D. in Pharmacoepidemiology, Epidemiology, Biostatistics or related field. 

  • Experience with the following: target trial emulation, sequential trial analysis, marginal structural models, longitudinal matching, G methods, or equivalent causal inference methods realized in at least 2 primary-author peer-reviewed publications, or equivalent. 

  • Ability to independently conduct statistical analysis with analytic software tools (e.g. Python, R, SQL, MatchIt/WeightIt, Matplotlib, Lifelines, SKLearn, GT-summary, statsmodels, Survey). 

  • Fluent in coding languages and tools (e.g. Python, R, SQL, Spark). 

  • Strong communication and collaboration skills, with the ability to work effectively in a multidisciplinary team. 

 

Preferred Qualifications:

  • Experience with meta-analyses and/or systematic reviews. 

  • Expertise in best practices for statistical approaches, data wrangling and visualization. 

  • Knowledge of FAIR data principles. 

  • Clinical informatics experience. 

 

 

Disclaimer: The above description is meant to illustrate the general nature of work and level of effort being performed by individuals assigned to this position or job description. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job description or responsibilities as needed.

The diversity of Axle’s employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment based on age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate.

Accessibility: If you need an accommodation as part of the employment process please contact: careers@axleinfo.com

This role has a market-competitive salary with an anticipated base compensation range listed below. Actual salaries will vary depending on a candidate’s experience, qualifications, skills, and location.

#INDPSD

Salary Range
$135,000—$140,000 USD

High-Performance Computing (HPC) Systems Engineer

(ID: 2025-0683)

Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations nationally and abroad. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).

 

Axle is seeking a High-Performance Computing (HPC) Systems Engineer to join our vibrant team at the National Institutes of Health (NIH) supporting the The National Center for Advancing Translational Sciences (NCATS) located in Rockville, MD.

 

Benefits We Offer:

  • 100% Medical, Dental & Vision Coverage for Employees
  • Paid Time Off and Paid Holidays
  • 401K match up to 5%
  • Educational Benefits for Career Growth
  • Employee Referral Bonus
  • Flexible Spending Accounts:
    • Healthcare (FSA)
    • Parking Reimbursement Account (PRK)
    • Dependent Care Assistant Program (DCAP)
    • Transportation Reimbursement Account (TRN)

 

Overview: 

The High-Performance Computing (HPC) Systems Engineer will support the Scientific Computing and Informatics (SCI) team at The National Center for Advancing Translational Sciences (NCATS). This role will focus on the design, optimization, security, and maintenance of HPC and cloud-based infrastructures that enable cutting-edge biomedical research through scalable, secure, and high-performing computing environments. 

 

 

Responsibilities: 

  • Design, configure, and maintain scalable HPC clusters for optimal performance. 

  • Support documentation and ATO (Authority to Operate) processes. 

  • Ensure infrastructure design compliance with federal security standards and best practices. 

  • Implement monitoring tools such as XDMoD for transparency and user reporting. 

  • Integrate platforms such as JupyterHub and job schedulers (e.g., Slurm) for improved interactivity. 

  • Develop and manage AWS-based infrastructure using Terraform, Packer, and Ansible. 

  • Automate deployment workflows to streamline provisioning, updates, and scaling. 

  • Manage systems involved in AWS Secure Cloud Bridging (SCB) and STRIDES initiatives. 

  • Implement CIS benchmark-aligned system hardening using OpenSCAP. 

  • Administer optimized compute images (CPU/GPU) for scientific workflows. 

  • Leverage tools such as OpenHPC, Warewulf, and Ansible for environment management. 

  • Lead and coordinate quarterly patch cycles. 

  • Partner with researchers and external stakeholders on critical projects. 

  • Facilitate solution transitions to other NIH centers and collaborators. 

  • Contribute to publications and team objectives through deep technical engagement. 

 

 

Qualifications: 

  • Federal ATO processes experience required 

  • HPC architecture and performance optimization is required 

  • Scientific software development and deployment 

  • High-speed network and parallel file system architecture 

  • Troubleshooting, diagnostics, and technical support 

  • Strong communication and multitasking skills 

  • Programming & Scripting:  

  • Languages – Pascal, BASIC, Delphi, Visual Basic, C, C++ 

  • Scripting – Bash, Perl, Python, Ruby, PEAR, Tcl 

  • Systems & Network Administration:  

  • Linux – RHEL/CentOS, SUSE, Debian, Ubuntu 

  • Windows – 95–10; NT–Server 2016 

  • Networking – Active Directory, TCP/IP v4/v6, DHCP, DNS, WINS 

  • Legacy – NOVELL 3.1–5, VPN, Citrix, Terminal Services 

  • Monitoring & Management Tools:  

  • Nagios, Ganglia, HP BAC, Precise i3 

  • SGI SMC, HP PCM, Bright Cluster Manager (incl. Data Analytics) 

  • Infrastructure & Automation:  

  • Puppet, Cobbler, Ansible, Chef 

  • Red Hat Satellite, Kickstart, RPM optimization 

  • File Systems & Archiving:  

  • Panasas (DirectFlow/panfs), DDN (GPFS), SGI DMF, StorHouse/RFS (Filetek) 

  • HPC Tools & Job Scheduling:  

  • MOAB/MAUI, Torque, PBS Pro, Windows HPC Scheduler 

  • Visualization & Remote Access:  

  • Nice DCV, EnginFrame, VNC, OpenText Exceed OnDemand, Web Remote Desktop 

  • Containerization & GPU:  

  • Docker, Kubernetes, Kubeflow, NVIDIA DGX-1 GPU systems 

  • Databases:  

  • SQL Server (2000–2008), MySQL, Zope 

  • High-Speed Networking:  

  • Infiniband, Mellanox, OFED, Voltaire, Force10 

  • Proven experience in: 

  • HPC architecture and performance tuning 

  • Cybersecurity in HPC/cloud environments 

  • Infrastructure as Code (AWS, Terraform, Ansible, Packer) 

  • Supporting scientific workflows in research environments 

 

 

 

Disclaimer: The above description is meant to illustrate the general nature of work and level of effort being performed by individuals assigned to this position or job description. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job description or responsibilities as needed.

The diversity of Axle’s employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment based on age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate.

Accessibility: If you need an accommodation as part of the employment process please contact: careers@axleinfo.com

This role has a market-competitive salary with an anticipated base compensation range listed below. Actual salaries will vary depending on a candidate’s experience, qualifications, skills, and location.

#INDPSD

Salary Range
$150,000—$160,000 USD

Senior Healthcare Data Engineer

(ID: 2025-0413)

Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations nationally and abroad. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).

 

Axle is seeking a Senior Healthcare Data Engineer to join our vibrant team at the National Institutes of Health (NIH) supporting the National Center for Advancing Translation Sciences (NCATS) located in Rockville, MD.

 

Benefits We Offer:

  • 100% Medical, Dental & Vision Coverage for Employees
  • Paid Time Off and Paid Holidays
  • 401K match up to 5%
  • Educational Benefits for Career Growth
  • Employee Referral Bonus
  • Flexible Spending Accounts:
    • Healthcare (FSA)
    • Parking Reimbursement Account (PRK)
    • Dependent Care Assistant Program (DCAP)
    • Transportation Reimbursement Account (TRN)

 

Key Responsibilities:

Design and Automation of Data Pipelines: 

  • Build and maintain scalable and efficient data pipelines for clinical and research datasets. 

  • Automate the extraction, transformation, and loading (ETL) processes to ensure timely and reliable data delivery, while optimizing workflows for downstream analysis.

Data Ingestion, Standardization, and Harmonization: 

  • Ingest large-scale datasets from diverse clinical and research sources. 

  • Collaborate with data science teams to harmonize data across systems

  • Implement best practices for cleaning and standardizing data to enable consistent analytics.

Standards Compliance and Modeling: 

  • Ensure datasets meet healthcare and research compliance requirements by aligning data with established Common Data Models such as CDISC and OMOP. 

  • Work closely with clinical data teams to maintain integrity and usability of standardized datasets.

Workflow Development and Reproducibility: 

  • Develop, optimize, and automate workflows using tools like Snakemake or Nextflow. 

  • Containerize pipelines using Docker to support reproducibility and scalability across research and production environments.

  • Promote continuous integration and deployment within data workflows.

Collaboration and Documentation: 

  • Work closely with multidisciplinary teams including data scientists, biostatisticians, and software engineers to align data infrastructure with project needs. 

  • Maintain comprehensive documentation of pipeline architectures and workflow logic to ensure clarity, transparency, and reproducibility.

Required:

  • Bachelor’s degree in computer science, Data Engineering, Bioinformatics, or a related field, with 6-10+ years of relevant experience; or a Master’s degree with 4-7 years of experience.

  • Proven ability to design, build, and maintain scalable data pipelines and automate ETL processes.

  • Hands-on experience working with clinical or research data and familiarity with healthcare data standards and Common Data Models (e.g., CDISC, OMOP).

  • Familiarity with big data frameworks like Apache Spark or Hadoop.

  • Strong skills in Python, SQL, and shell scripting (e.g., Bash).

  • Experience using Docker to containerize data workflows for reproducibility and scalability.

  • Proficiency with version control systems like Git and continuous integration practices.

Preferred:

  • Experience with cloud platforms (e.g., AWS, GCP, Azure) for large-scale data processing.

  • Proficiency with workflow management systems such as Snakemake, Nextflow, or similar tools.

 

Disclaimer: The above description is meant to illustrate the general nature of work and level of effort being performed by individuals assigned to this position or job description. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job description or responsibilities as needed.

The diversity of Axle’s employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment based on age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate.

Accessibility: If you need an accommodation as part of the employment process please contact: careers@axleinfo.com

This role has a market-competitive salary with an anticipated base compensation range listed below. Actual salaries will vary depending on a candidate’s experience, qualifications, skills, and location.

#INDPSD

Salary Range
$115,000—$155,000 USD

Senior Full Stack Developer

(ID: 2025-0609)

Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations nationally and abroad. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).

 

Axle is seeking a Senior Full Stack Developer to join our vibrant team at the National Institutes of Health (NIH) supporting the National Center for Advancing Translation Sciences (NCATS) located in Rockville, MD.

 

Benefits We Offer:

  • 100% Medical, Dental & Vision Coverage for Employees
  • Paid Time Off and Paid Holidays
  • 401K match up to 5%
  • Educational Benefits for Career Growth
  • Employee Referral Bonus
  • Flexible Spending Accounts:
    • Healthcare (FSA)
    • Parking Reimbursement Account (PRK)
    • Dependent Care Assistant Program (DCAP)
    • Transportation Reimbursement Account (TRN)

Overview:

At Axle Informatics, we work with a number of different clients across the federal space, including the National Center for Advancing Translational Sciences (NCATS) within the National Institutes of Health (NIH). You will be working with a diverse team of full-stack developers, cloud engineers, and subject matter experts to design and build NCATS Notebooks Hub, a cloud-native solution for managing and enabling data analysis and data exploration through interactive developer environments (IDEs) and custom-built dashboarding and visualization applications. Our pipeline utilizes modern containerization and container orchestration tools in a cloud-based platform. 

Qualifications:

  • Bachelor’s Degree in Computer Science, Data Science, Bioinformatics or other related field (years of work experience will be considered in lieu of degree)
  • 3+ years experience working with TypeScript/JavaScript
  • 3+ years experience as a full-stack developer
  • Experience with the following is preferred:
    • Node.js
    • Angular 19+
    • NoSQL databases (MongoDB)
    • Containers and container orchestration tools (Docker, Kubernetes)
    • DevOps tools (Jenkins, GitHub Actions)
  • Familiarity with VCS such as Git
  • Experience with unit and end-to-end testing frameworks
  • Experience with using and leveraging GenAI technologies (i.e., CursorAI, Cline, Windsurf)

 

Relevant Skills:

 

  • Critical thinking, problem solving, and attention to detail
  • Clear, concise communication
  • Technical writing ability
  • Familiarity working in an Agile environment
  • Attention to detail when building visually appealing and intuitive UI

Responsibilities:

  • Build scalable, reliable, and flexible applications in TypeScript using NodeJS and Angular 9+
  • Design, implement, and/or use RESTful web services
  • Implement modern and responsive UI for the web and variety of devices
  • Participate in agile software development, prototyping, testing, and code reviews with a small team of developers
  • Write robust unit and end-to-end tests

 

Disclaimer: The above description is meant to illustrate the general nature of work and level of effort being performed by individuals assigned to this position or job description. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job description or responsibilities as needed.

The diversity of Axle’s employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment based on age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate.

Accessibility: If you need an accommodation as part of the employment process please contact: careers@axleinfo.com

This role has a market-competitive salary with an anticipated base compensation range listed below. Actual salaries will vary depending on a candidate’s experience, qualifications, skills, and location.

#INDPSD

Salary Range
$120,000—$145,000 USD

Scientific Program Manager

(ID: 2025-0257)

Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations around the globe. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).

Benefits:

  • 100% Medical, Dental & Vision Coverage for Employees
  • Paid Time Off (Including Holidays)
  • Employee Referral Bonus
  • 401K Match
  • Tuition reimbursement and professional development opportunities
  • Flexible Spending Accounts:
    • Healthcare (FSA)
    • Parking Reimbursement Account (PRK)
    • Dependent Care Assistant Program (DCAP)
    • Transportation Reimbursement Account (TRN)

Overview

Axle is looking to add a driven, flexible, organized, and meticulous Scientific Program Manager to our dynamic team. The Contractor(s) shall provide services in support of the overall functions of the Vaccine Research Center (VRC), Vaccine Production Program (VPP). 

 

Technical Requirements:

  • Conduct and participate in projects that are complex and scientifically demanding within a specific area/field. Specialty requirement in mass spectrometry.

  • Initiate, implement, plan, direct, and execute scientific research and development.

  • Make detailed observations, analyze data, and interpret results. Demonstrate scientific rigor in assessing own data and that of others.

  • Responsible for meeting project goals within time and budget constraints.

  • Demonstrate ability for scientific insight and conceptual thinking.

  • Independently plan, design, evaluate, revise and execute projects within RP-HPLC and LC-MS filed, utilizing good scientific judgment. Lead specific investigation and method development work in support of multiple projects at a time.

  • Develop research findings and makes recommendations.

  • Effectively present and participate results at internal meetings.

  • Lead investigations and write manuscripts to publish state of art work

  • Utilize forward-looking perspective to contribute to “go/no go” decisions.

  • Make recommendations on outside technologies for company to pursue.

  • Project area includes monoclonal antibody and multi-specific antibody; recombinant protein vaccine and nanoparticles; mRNA and mRNA/LNP vaccines.

  • Analytical skills and applications include but not limited to develop release and characterization method by utilizing reversed phase HPLC/or UPLC -UV methods, and HPLC/or UPLC/or nanoLC – MS methods for pipeline project support.

 

Specific Qualifications:

  • Ph.D. in a scientific field 10+ years of specialized experience

  • Deep understanding challenges and method development approaches of mAb, vaccine and mRNA scientific field

  • Demonstrates expert knowledge working in the research/development laboratory environment.

  • Must be a team player who can effectively work with members from cross-functional departments.

  • Demonstrated knowledge of maintaining accurate and detailed records.

  • Strong oral and written communication skills.

  • Familiarity with computer software including word processing, data evaluation, and project timeline management.

The diversity of Axle’s employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment-based age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate.

Accessibility: If you need an accommodation as part of the employment process please contact: careers@axleinfo.com

Disclaimer: The above description is meant to illustrate the general nature of work and level of effort being performed by individual’s assigned to this position or job description. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job description or responsibilities as needed.

This role has a market-competitive salary with an anticipated base compensation range listed below. Actual salaries will vary depending on a candidate’s experience, qualifications, skills, and location.

#INDPSD

Salary Range
$120,000—$135,000 USD

Scientific Program Manager

(ID: 2025-0639)

Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations nationally and abroad. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).

 

Axle is seeking a Scientific Program Manager to join our Program Coordination Team to support the National Institutes of Health (NIH) initiative to advance standardized organoid model development.  The Scientific Program Manager will oversee key program goals to improve the rate of successful organoid model development, ensure seamless collaboration with internal and external groups, work closely with the Organoid Development Lab, continuously improve operations supporting the organoid lifecycle, work to meet and then exceed metrics for program performance.

 

Benefits We Offer:

  • 100% Medical, Dental & Vision Coverage for Employees
  • Paid Time Off and Paid Holidays
  • 401K match up to 5%
  • Educational Benefits for Career Growth
  • Employee Referral Bonus
  • Flexible Spending Accounts:
    • Healthcare (FSA)
    • Parking Reimbursement Account (PRK)
    • Dependent Care Assistant Program (DCAP)
    • Transportation Reimbursement Account (TRN)

 

Overview:

The core function of this role is to help the laboratory establish, optimize, and continuously improve logistics — spanning biospecimen acquisition, processing, storage, data management, and resource sharing — while also developing and maintaining the overall program plan. This position will serve as a central hub between scientific teams, external collaborators, administrative staff, to ensure efficient logistics, program-level coordination, regulatory compliance, and high-impact outcomes. The Scientific Program Manager will provide scientific, operational, and logistical leadership across complex, multi-institutional projects. Responsibilities include:

 

Responsibilities:

  • Program & Project Management
    • Develop and maintain the overall program plan, ensuring alignment across all projects, milestones, and deliverables.
    • Create and manage detailed project plans, including timelines, budgets, and logistical workflows.
    • Apply project management best practices to track progress, manage risks, and drive resolution across a matrixed team of researchers, clinicians, and collaborators.
    • Support protocol standardization, logistics optimization, and quality control implementation across programs.
  • Biospecimen Lifecycle & Logistics
    • Lead the end-to-end logistics of the biospecimen lifecycle, including compliant acquisition, processing, storage, distribution, and documentation of high-quality samples.
    • Establish and continuously improve laboratory logistics systems to ensure standardization, efficiency, and reproducibility.
    • Coordinate with clinical partners and biorepositories to ensure traceability, ethical compliance, and regulatory alignment (IRB approvals, consent, data sharing agreements).
  • Collaboration & Stakeholder Engagement
    • Act as a liaison between scientific teams, external collaborators, and federal stakeholders, ensuring effective communication and coordination.
    • Facilitate cross-collaboration with the Organoid Development Lab to align goals, share resources, and support harmonized workflows.
    • Organize scientific meetings, workshops, and outreach events to promote collaboration and program visibility.
  • Reporting & Compliance
    • Prepare progress reports, presentations, and documentation to meet NIH requirements.
    • Contribute to grant submissions, project deliverables, and stakeholder communications.
    • Support the implementation of data management best practices, including data standardization, sharing, and compliance with FAIR principles.

 

Required Qualifications:

  • Ph.D. in biology, bioengineering, stem cell biology, pharmacology, or a related biomedical field.
  • Minimum 3 years of experience in scientific project or program management within academia, government, or industry.
  • Strong foundation in organoid technologies, 3D cell culture, or human disease modeling.
  • Demonstrated expertise in biospecimen lifecycle management and laboratory logistics.
  • Experience managing interdisciplinary research initiatives or multi-institutional collaborations.
  • Proven ability to develop and maintain overall program plans, track milestones, coordinate logistics, and support operational efficiency.
  • Working knowledge of biobanking practices, ethical compliance, and regulatory frameworks for human tissue acquisition.
  • Effective communication skills with both scientific and non-scientific audiences.
  • Familiarity with regulatory processes (IRB, MTAs, data sharing agreements).
  • Experience contributing to grant proposals, reports, or federally required documentation.

 

Preferred Qualifications:

  • Prior experience in federally funded research programs (e.g., NIH consortia such as RMIP, HuBMAP, BRAIN, NCATS).
  • Background in biospecimen lifecycle coordination, clinical partnerships, or biorepository oversight.
  • Proficiency in project management methodologies and tools (e.g., Gantt charts, Asana, Smartsheet).
  • Formal project management certification (PMP, CAPM, or equivalent).
  • Experience in data standardization, data sharing workflows, or FAIR principles in biomedical research.
  • Demonstrated ability to navigate complex stakeholder environments, balance competing priorities, and deliver outcomes in a fast-paced, multidisciplinary setting.

 

Disclaimer: The above description is meant to illustrate the general nature of work and level of effort being performed by individuals assigned to this position or job description. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job description or responsibilities as needed.

The diversity of Axle’s employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment based on age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate.

Accessibility: If you need an accommodation as part of the employment process please contact: careers@axleinfo.com

This role has a market-competitive salary with an anticipated base compensation range listed below. Actual salaries will vary depending on a candidate’s experience, qualifications, skills, and location.

#INDPSD

Salary Range
$150,000—$170,000 USD

Scientific Project Manager

(ID: 2025-0682)

Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations nationally and abroad. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).

 

Axle is seeking a Scientific Project Manager to join our Program Coordination Team to support the National Institutes of Health (NIH) initiative to advance standardized organoid model development. This effort aims to expedite the use of organoid models in biomedical research and human health.

 

Benefits We Offer:

  • 100% Medical, Dental & Vision Coverage for Employees
  • Paid Time Off and Paid Holidays
  • 401K match up to 5%
  • Educational Benefits for Career Growth
  • Employee Referral Bonus
  • Flexible Spending Accounts:
    • Healthcare (FSA)
    • Parking Reimbursement Account (PRK)
    • Dependent Care Assistant Program (DCAP)
    • Transportation Reimbursement Account (TRN)

 

Overview:

The Scientific Project Manager will contribute to both the initial setup and ongoing execution of the scientific and quality objectives established for the Coordinating Center. The successful candidate will be a collaborative team player who is professional, organized, and enthusiastic about contributing to this groundbreaking initiative. In addition to project coordination, the role will involve facilitating and conducting analyses of program-generated data. The Scientific Project Manager will play a central role in scientific and operational coordination to advance standardized organoid model development. 

 

Responsibilities: 

  • Developing and implementing standardized processes for the biospecimen lifecycle, ensuring alignment with scientific and regulatory best practices.
  • Monitoring project timelines, deliverables, and risk management strategies to support the development and adoption of standardized Standard Operating Procedures (SOPs).
  • Leading SOP development, review, and governance, including version control and continuous improvement.
  • Ensuring compliance with consent and regulatory requirements, while facilitating adherence across collaborating sites.
  • Coordinating data analysis and integration efforts, ensuring accurate and timely reporting of program outcomes.
  • Adapting to evolving responsibilities as the project progresses, demonstrating flexibility and a commitment to learning new skills.

 

Qualifications: 

  • Advanced degree (M.S. or Ph.D.) in genetics, cell biology, molecular biology, bioengineering, or a related discipline.
  • At least 5 years of experience managing projects involving clinical data and biospecimens.
  • Demonstrated expertise in scientific program management, including SOP or quality system development and implementation.
  • Strong scientific communication skills (written and oral).
  • Ability to track budgets and financial information in support of program administration.
  • Experience drafting statements of work, negotiating subcontracts, and collaborating with subcontract specialists.

 

Disclaimer: The above description is meant to illustrate the general nature of work and level of effort being performed by individuals assigned to this position or job description. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job description or responsibilities as needed.

The diversity of Axle’s employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment based on age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate.

Accessibility: If you need an accommodation as part of the employment process please contact: careers@axleinfo.com

This role has a market-competitive salary with an anticipated base compensation range listed below. Actual salaries will vary depending on a candidate’s experience, qualifications, skills, and location.

#INDPSD

Salary Range
$120,000—$140,000 USD

Scientific Project Manager

(ID: 2025-0631)

Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations nationally and abroad. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).

 

Axle is seeking a Scientific Project Manager to join our Program Coordination Team in support of the National Institutes of Health (NIH) initiative to advance standardized organoid model development. This initiative aims to expedite the use of organoid models in biomedical research and human health. 

 

Benefits We Offer:

  • 100% Medical, Dental & Vision Coverage for Employees
  • Paid Time Off and Paid Holidays
  • 401K match up to 5%
  • Educational Benefits for Career Growth
  • Employee Referral Bonus
  • Flexible Spending Accounts:
    • Healthcare (FSA)
    • Parking Reimbursement Account (PRK)
    • Dependent Care Assistant Program (DCAP)
    • Transportation Reimbursement Account (TRN)

 

Overview:

The Scientific Project Manager will contribute to both the initial setup and ongoing execution of the scientific and quality objectives established for the Coordinating Center. The successful candidate will be a collaborative team player who is professional, organized, and enthusiastic about contributing to this groundbreaking initiative. In addition to coordinating project activities, the role will involve organizing and facilitating meetings with scientific leaders, guiding the validation of Standard Operating Procedures (SOPs), and supporting project planning, reporting, and documentation of Data Repository requirements. The Scientific Project Manager will play a central role in scientific and operational coordination to advance standardized organoid model development.

 

Responsibilities:

  • Planning, organizing, and facilitating meetings with scientific leaders and stakeholders, ensuring alignment of program goals and fostering collaborative decision-making.
  • Developing project plans and tracking progress, including timelines, milestones, and deliverables, to ensure successful execution of program objectives.
  • Guiding SOP validation processes, including the design of validation strategies, collection of stakeholder input, and documentation of outcomes to ensure robustness and reproducibility. Developing reports, presentations, and documentation, including tracking and reporting on Data Repository requirements to ensure compliance with NIH data sharing expectations.
  • Defining, documenting, and coordinating Data Repository needs, including standards for data submission, quality control, and metadata requirements.
  • Developing and implementing standardized processes for the biospecimen lifecycle, ensuring adherence to scientific and regulatory best practices.
  • Leading SOP development, review, and governance, including version control, quality assurance, and continuous improvement.
  • Monitoring project risk management strategies and ensuring timely resolution of barriers.
  • Ensuring compliance with consent and regulatory requirements, while facilitating adherence across collaborating sites.
  • Coordinating data analysis and integration efforts, ensuring accurate and timely reporting of program outcomes.
  • Adapting to evolving responsibilities as the project progresses, demonstrating flexibility and a commitment to learning new skills. 

 

Qualifications: 

  • Advanced degree (Ph.D.) in genetics, cell biology, molecular biology, bioengineering, or a related discipline.
  • At least 5 years of experience managing projects involving clinical data and biospecimens.
  • Demonstrated expertise in scientific program management, including SOP or quality system development, implementation, and validation.
  • Proven ability to develop project plans, reports, and documentation of Data Repository requirements in alignment with NIH expectations.
  • Strong scientific communication and facilitation skills, with the ability to lead meetings involving senior scientific stakeholders.
  • Ability to track budgets and financial information in support of program administration.
  • Experience drafting statements of work, negotiating subcontracts, and collaborating with subcontract specialists.
  • Project Management Professional (PMP) certification.
  • Experience with organoid systems, tissue engineering, or related biological models.
  • Prior involvement in large-scale, multi-institutional collaborative research projects.
  • Familiarity with NIH data sharing policies, repository submission requirements, and compliance frameworks.

 

Disclaimer: The above description is meant to illustrate the general nature of work and level of effort being performed by individuals assigned to this position or job description. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job description or responsibilities as needed.

The diversity of Axle’s employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment based on age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate.

Accessibility: If you need an accommodation as part of the employment process please contact: careers@axleinfo.com

This role has a market-competitive salary with an anticipated base compensation range listed below. Actual salaries will vary depending on a candidate’s experience, qualifications, skills, and location.

#INDPSD

Salary Range
$120,000—$140,000 USD