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Job Location: Bethesda, MD

Bioinformatics Scientist

(ID: 2026-1976)
 
Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations nationally and abroad. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).

Benefits We Offer:

  • 100% Medical, Dental & Vision Coverage for Employees
  • Paid Time Off and Paid Holidays
  • 401K match up to 5%
  • Educational Benefits for Career Growth
  • Employee Referral Bonus
  • Flexible Spending Accounts:
    • Healthcare (FSA)
    • Parking Reimbursement Account (PRK)
    • Dependent Care Assistant Program (DCAP)
    • Transportation Reimbursement Account (TRN)

Axle is seeking a highly ambitious, adaptable, structured, and detail-oriented Bioinformatics Scientist to join our vibrant team at the National Institutes of Health (NIH), National Institute of Allergy and Infectious Diseases (NIAID), Division of Intramural Research (DIR), Research Technologies Branch (RTB), Integrated Data Sciences Section (IDSS) in Bethesda, MD. 

 
Responsibilities:

  • Address bioinformatics, scientific computing, and data analysis needs of users within the Division of Intramural Research (DIR) at NIAID and their collaborators by lending expertise in the proper statistical design of biological experiments involving high-throughput genome-scale technologies, data mining and knowledge discovery techniques, automated workflow development, statistical and scientific experimental design consulting.
  • Provide bioinformatics support to include somatic and germline variant calling and analysis, single-cell and bulk gene expression analysis, de novo assembly of genomes and transcriptomes, comparative genomics of model and non-model organisms, proteomics, ChIP-seq, ATAC-seq, and the development of high-throughput pipelines for the analysis of the above data modalities.
  • Provide programming and troubleshooting support to the Research Technologies Branch (RTB) of the National Institute of Allergy and Infectious Diseases (NIAID) and collaborating Institutes in the dissemination of research data.
  • Perform computational data analysis on genomic and clinical research data.
  • Work with staff on scientific programming and experimental design. Provide statistical support/analysis on research data.
  • Contribute to and co-author scientific publications in leading peer-reviewed journals.
  • Contribute to the development of a scalable and flexible resource to provide NGS bioinformatics, structural biological and computational, machine learning data support to NIAID scientists and investigators.
  • It is expected that the bioinformatics scientist will need strong skills in the following:
    • NGS analysis (whole-exome, whole-genome, RNA-seq, ChIP-Seq, both long- and short-read technologies, etc.)
    • Statistical modeling
    • Scripting
    • Biological interpretation

Specific Qualifications:

  • Ability to obtain and maintain a Public Trust Security clearance
  • Minimum Bachelor’s degree in related field, Master’s or Ph.D. preferred
  • 4+ years of experience in bioinformatics
  • 2+ years of experience developing and maintaining production bioinformatics pipelines
  • Expert in two (2) of the following languages: Python, R, C/C++, sh/bash
  • Experience building images using one (1) of the following: Docker, Podman, Singularity/Apptainer
  • Expert in one (1) pipeline framework: Snakemake, Nextflow, CWL/WDL
  • Expertise building technical and user documentation for tools, pipelines, and applications
  • Experience building pipelines locally on-premise using available HPC infrastructure
  • Experience building pipelines/applications in the Cloud with AWS/GCP/Azure is a plus
  • Experience building applications using one (1) of the following frameworks is a plus: Django, Flask, RShiny, Electron, Flutter, React
  • Experience working in a laboratory setting is a plus but not required

 

Disclaimer: The above description is meant to illustrate the general nature of work and level of effort being performed by individuals assigned to this position or job description. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job description or responsibilities as needed.

The diversity of Axle’s employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment based on age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate.

Accessibility: If you need an accommodation as part of the employment process please contact: careers@axleinfo.com

This role has a market-competitive salary with an anticipated base compensation range listed below. Actual salaries will vary depending on a candidate’s experience, qualifications, skills, and location.

Salary Range
$120,000—$130,000 USD

Single Cell Biologist

(ID: 2026-1837)

Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations nationally and abroad. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).

Axle is seeking a Single Cell Biologist to join our vibrant team at the National Institutes of Health (NIH) supporting the National Institute on Aging (NIA) located in Bethesda, MD.

Benefits We Offer:

  • 100% Medical, Dental & Vision Coverage for Employees
  • Paid Time Off and Paid Holidays
  • 401K match up to 5%
  • Educational Benefits for Career Growth
  • Employee Referral Bonus
  • Flexible Spending Accounts:
    • Healthcare (FSA)
    • Parking Reimbursement Account (PRK)
    • Dependent Care Assistant Program (DCAP)
    • Transportation Reimbursement Account (TRN)

Position Information:

 

This single cell biologist supports research at the Center for Alzheimer’s and Related Dementias by processing human tissue and cell lines, preparing sequencing libraries and analyzing data.

 

Deliverables:

  • Clean Equipment – Daily

  • Run Validation – Daily

  • Inspect Equipment – Weekly

  • Meet with lab members to present updates – Bi-Weekly

 

Statement of Work Details:

  • Monitor operational procedures in technical environments to ensure conformance to standards – 1
  • Record research or operational data – 2
  • Interpret research or operational data – 3
  • Program and use computers to store, process, and analyze data – 4
  • Operate laboratory equipment to analyze samples – 5

  • Provides technical experience needed to assist in studying the basic principles of plant and animal life

  • Plan and administer biological research programs

  • Study basic principles of plant and animal life, such as origin, relationship, development, anatomy, and function

  • Develop and maintain liaisons and effective working relations with groups and individuals, agencies, and the public to encourage cooperative management strategies or to develop information and interpret findings

  • Assists with performing basic laboratory experiments and procedures

  • Collect and analyze biological data about relationships among and between organisms and their environment

  • Monitor and observe experiments, recording production and test data for evaluation by research personnel

  • Analyze experimental data and interpret results to write reports and summaries of findings

  • Coordinate the work of biological technicians and technologists and other scientists

  • Prepares, organizes and maintains various lab samples, supplies, and equipment

  • Operate, calibrate, or maintain equipment used in quantitative or qualitative analysis, such as spectrophotometers, calorimeters, flame photometers, or computer-controlled analyzers

  • Maintain laboratory equipment

  • Analyze laboratory findings

  • Learns new laboratory techniques and procedures

 

Certifications & Licenses

  • Good Laboratory Practices (GLP)

 

Field of Study

  • Genetics

  • Neuroscience

  • Molecular Biology

 

Software

  • Outlook

  • Seurat

  • R

  • Excel

  • Google Drive

  • PowerPoint

 

Skills

  • QC testing

  • Planning and optimizing experiments

  • Sequencing samples

  • Library Prep

 

Disclaimer: The above description is meant to illustrate the general nature of work and level of effort being performed by individuals assigned to this position or job description. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job description or responsibilities as needed.

The diversity of Axle’s employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment based on age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate.

Accessibility: If you need an accommodation as part of the employment process please contact: careers@axleinfo.com

This role has a market-competitive salary with an anticipated base compensation range listed below. Actual salaries will vary depending on a candidate’s experience, qualifications, skills, and location.

Salary Range
$95,000—$106,234.51 USD

Veterinarian

(ID: 2026-1777)

Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations nationally and abroad. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).

Axle is seeking a Veterinarian to join our vibrant team at the National Institutes of Health (NIH) supporting the Clinical Center (CC) located in Bethesda, MD.

Benefits We Offer:

  • 100% Medical, Dental & Vision Coverage for Employees
  • Paid Time Off and Paid Holidays
  • 401K match up to 5%
  • Educational Benefits for Career Growth
  • Employee Referral Bonus
  • Flexible Spending Accounts:
    • Healthcare (FSA)
    • Parking Reimbursement Account (PRK)
    • Dependent Care Assistant Program (DCAP)
    • Transportation Reimbursement Account (TRN)

Position Information:

 

The purpose of this position is to manage small animals care, handling and procedures used for research in a lab conducting computer-based PET/CT imaging. The person is also responsible for maintaining and operating laboratory equipment in the microPET area; help plan and perform research studies; ordering and maintaining the necessary lab supplies; train new personnel with proper use and methods associated with animal experiments; developing and test new animals models based on research needs. Daily monitoring of animal health for long term studies that includes occasional weekends and coordinating with animal facilities for experiments.

 

Additional Qualifications:

 

Certifications & Licenses

  • N/A

 

Field of Study

  • Animal Sciences
  • Microbiology
  • Pharmacology

 

Software

  • Knowledge of computer usage for data collection and analysis, and a knowledge of PET/CT scanner operations and software

 

Skills

  • Knowledge of small animal PET/CT imaging procedures/ processes
  • Training new lab personnel in various animal procedures
  • Daily monitoring of animals on long-term studies
  • Planning and coordinating with animal facilities for experiments
  • Animal handling and various inoculation procedures

 

Deliverables:

 

  • Inspect Equipment – Ad-Hoc
  • Meet with lab members to present updates – Weekly
  • Monitor animal health and perform clinical scoring – Ad-Hoc
  • Maintain files on studies being performed in the facility as well as records of radioactive material administered for Radiation Safety inspections – Monthly

 

Statement of Work Details: 

 

  • Develops research protocols involving animals. – 1
  • Performs research and documents findings. – 2
  • Documents all findings and develops reports of results. – 3
  • Monitor the experiment conditions and make recommendations to researchers on appropriate care and treatment of experiment animals. – 4
  • Documents all experimental procedures and reports findings as necessary. – 5
  • Provides routine medical care to research colonies.
  • Perform non-diagnostic checks of animal health and wellness.
  • Provide vaccinations and inoculations to prevent diseases.
  • Perform animal surgeries.
  • Perform surgical procedures on facility animals, as needed, (spa and neuter, hernia repair, growth removals, dental extractions, etc.).
  • Provide post operative care of all animals.
  • Perform euthanizations as necessary.
  • Conduct postmortem studies and analyze findings.
  • Maintains accurate records and updates databases.
  • Maintain accurate and complete medical records, including those recorded in the facility database (including treatments, examinations, test results, surgeries and outcomes) and other records required by local and state laws.
  • Monitor animals involved in drug therapies and treatments for responsiveness and treatment performance and document findings.
  • Determine and document the effects of drug therapies, antibiotics and new surgical techniques.
  • Provide routine reporting on animal status to researchers and staff.
  • Ensures facility compliance with federal, state, local and departmental laws, regulations and guidelines.
  • Maintain all established shelter medical standards, such as drug log and security record, cleaning protocols, surgical procedures, medical protocols, etc.
  • Identify new regulatory requirements and facilitate changes to operations to ensure timely compliance.
  • Maintain research lab to ensure regulatory compliance Participates in small animal and non-human primate experiements.
     

Disclaimer: The above description is meant to illustrate the general nature of work and level of effort being performed by individuals assigned to this position or job description. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job description or responsibilities as needed.

The diversity of Axle’s employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment based on age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate.

Accessibility: If you need an accommodation as part of the employment process please contact: careers@axleinfo.com

This role has a market-competitive salary with an anticipated base compensation range listed below. Actual salaries will vary depending on a candidate’s experience, qualifications, skills, and location.

Salary Range
$90,000—$103,000 USD

Power Apps / Sharepoint Developer

(ID: 2026-1547)

Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations nationally and abroad. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).

 

Benefits We Offer:

  • 100% Medical, Dental & Vision Coverage for Employees
  • Paid Time Off and Paid Holidays
  • 401K match up to 5%
  • Educational Benefits for Career Growth
  • Employee Referral Bonus
  • Flexible Spending Accounts:
    • Healthcare (FSA)
    • Parking Reimbursement Account (PRK)
    • Dependent Care Assistant Program (DCAP)
    • Transportation Reimbursement Account (TRN)

 

Position Overview

Axle is hiring a mid-level PowerApps / SharePoint Developer to support the National Institutes of Health (NIH) in improving collaboration, automating workflows, and streamlining business processes. The ideal candidate will have strong hands-on experience building PowerApps solutions, configuring SharePoint Online sites, and integrating data from multiple sources to support research and administrative programs across NIH. This is an excellent role for someone looking to contribute directly to NIH’s mission while growing technical skills in the Microsoft Power Platform and federal IT environment.

 

Key Responsibilities

  • Develop and maintain PowerApps (Canvas and Model-Driven) applications that automate NIH business processes and enhance data accessibility. 

  • Design and configure SharePoint Online sites, lists, pages, and web parts to improve collaboration and document management. 

  • Create Power Automate workflows to streamline approvals, notifications, and data movement. 

  • Integrate Power Platform solutions with other Microsoft 365 tools (Teams, Outlook, Excel) and external data sources (SQL Server, SharePoint). 

  • Support troubleshooting, enhancements, and updates for existing PowerApps and SharePoint applications. 

  • Ensure app designs meet Section 508 accessibility and agency security guidelines (HHS IT standards). 

  • Work closely with business users and NIH staff to gather requirements, provide user support, and deliver clear documentation. 

  • Participate in testing, code reviews, and version control to maintain quality and consistency across solutions. 

 

Required Qualifications

  • Bachelor’s degree in Computer Science, Information Systems, or a related field. 

  • 3–5 years of professional experience developing with PowerApps and SharePoint Online. 

  • Proficiency in PowerApps formulas, Power Automate flows, and SharePoint configuration. 

  • Solid understanding of data modeling, connectors, and integration with Microsoft 365 services. 

  • Experience using basic scripting or APIs (PowerShell, REST, or Microsoft Graph). 

  • Strong attention to detail, problem-solving ability, and communication skills. 

  • Ability to work onsite in Bethesda, MD 2 days a week. 
  • Ability to obtain and maintain a Public Trust clearance. 

 

Preferred Qualifications

  • Experience supporting HHS, NIH, or another federal health agency. 

  • Familiarity with Azure Active Directory, Dataverse, or SQL Server. 

  • Microsoft Certified: Power Platform App Maker Associate or similar certification. 

  • Basic understanding of HTML, CSS, or JavaScript for SharePoint UI customization. 

 

Why Join Us

At Axle, you’ll be part of a mission-driven team helping NIH harness technology to advance biomedical research and operational excellence. You’ll enjoy a collaborative, learning-focused environment with opportunities to expand your technical expertise in the Microsoft Power Platform ecosystem.

 

Disclaimer: The above description is meant to illustrate the general nature of work and level of effort being performed by individuals assigned to this position or job description. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job description or responsibilities as needed.

The diversity of Axle’s employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment based on age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate.

Accessibility: If you need an accommodation as part of the employment process please contact: careers@axleinfo.com

This role has a market-competitive salary with an anticipated base compensation range listed below. Actual salaries will vary depending on a candidate’s experience, qualifications, skills, and location.

#IND

Salary Range
$75,000—$85,000 USD