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Job Department: Biomedical

Program Associate

(ID: 2026-2381)

 

Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations nationally and abroad. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).

 

Benefits We Offer:

  • 100% Medical, Dental & Vision Coverage for Employees
  • Paid Time Off and Paid Holidays
  • 401K match up to 5%
  • Educational Benefits for Career Growth
  • Employee Referral Bonus
  • Flexible Spending Accounts:
    • Healthcare (FSA)
    • Parking Reimbursement Account (PRK)
    • Dependent Care Assistant Program (DCAP)
    • Transportation Reimbursement Account (TRN)

Position Summary

 

The Program Associate supports contract execution and operational delivery by ensuring accurate data management, process adherence, logistics coordination, and policy compliance. This execution-focused role maintains reliable contractual, financial, and operational data records while supporting project staff and structured reporting within the Service Delivery Unit (SDU).

 

Responsibilities

 

  • Execute assigned project tasks with strong attention to detail and strict adherence to established processes and operating workflows.

  • Accurately generate, enter, validate, and maintain secure data in enterprise systems.

  • Ensure precise project timesheet records in alignment with financial controls.

  • Maintain organized, audit-ready documentation in compliance with contractual requirements.

  • Generate and submit structured project records daily, weekly, monthly in support of data dashboards as needed.

  • Provide clear, professionally and effectively written communications to internal stakeholders

 

Required Qualifications

 

  • Bachelor’s degree in Business Administration, Public Administration, Project Management, or related field (or equivalent experience).

  • 2–4 years of experience in program operations, project management, or related administrative function.

  • Exceptional attention to detail with the ability to manage multiple priorities in a fast-paced environment.

  • Strong problem-solving and analytical skills.

  • Excellent interpersonal, oral, and written communication skills.

  • Independent technical performance with strong organizational and multitasking capabilities.

  • Familiarity with or exposure to artificial intelligence (AI) tools and data-driven technologies.

 

Preferred Qualifications

 

  • Ability to maintain documentation, support internal controls, and operate within structured, team-driven environments.

  • Exposure to project management frameworks (PMI/PMBOK fundamentals preferred).

  • Experience with dashboard tools (Power BI, Tableau, or similar

 

Disclaimer: The above description is meant to illustrate the general nature of work and level of effort being performed by individuals assigned to this position or job description. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job description or responsibilities as needed.

The diversity of Axle’s employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment based on age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate.

Accessibility: If you need an accommodation as part of the employment process please contact: careers@axleinfo.com

This role has a market-competitive salary with an anticipated base compensation range listed below. Actual salaries will vary depending on a candidate’s experience, qualifications, skills, and location.

Salary Range
$70,000—$80,000 USD

Data Science Fellow – AI/NLP

(ID: 2026-2316)

Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations nationally and abroad. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).

 

Benefits We Offer:

  • 100% Medical, Dental & Vision Coverage for Employees
  • Paid Time Off and Paid Holidays
  • 401K match up to 5%
  • Educational Benefits for Career Growth
  • Employee Referral Bonus
  • Flexible Spending Accounts:
    • Healthcare (FSA)
    • Parking Reimbursement Account (PRK)
    • Dependent Care Assistant Program (DCAP)
    • Transportation Reimbursement Account (TRN)

We are seeking a postdoctoral researcher to develop AI/NLP and knowledge engineering methods that transform biomedical literature, experimental protocols, and source evidence into structured, quarriable, and evidence-grounded knowledge for organoid protocol standardization and optimization. 

 

The postdoc will work at the intersection of large language models, biomedical NLP, scientific document understanding, knowledge graphs, ontology grounding, computational biology, and human-in-the-loop curation. Potential projects include LLM-based protocol extraction, retrieval-augmented literature mining, curated knowledge graph construction, ontology and entity normalization, protocol comparison, consensus protocol derivation, benchmark design, and natural-language interfaces over structured biological knowledge.

 

Responsibilities

 

  • Design and implement AI/NLP methods for biomedical literature mining and structured protocol knowledge extraction.

  • Develop benchmark datasets, annotation guidelines, and evaluation pipelines for scientific information extraction.

  • Build and evaluate RAG, in-context learning, fine-tuning, graph matching, entity normalization, and KG query workflows.

  • Analyze extraction errors, model behavior, retrieval failures, grounding quality, and biological ambiguity.

  • Collaborate with software engineers to integrate research methods into usable tools and reproducible pipelines.

  • Collaborate with organoid biologists and domain experts to translate biological protocol knowledge into computable representations.

  • Prepare manuscripts, conference abstracts, technical reports, design documents, and open-source research artifacts.

  • Help define research milestones, evaluation criteria, and publication strategy for protocol intelligence work.

 

Required Qualifications

 

  • PhD in computer science, computational biology, bioinformatics, biomedical informatics, NLP, machine learning, data science, or a related field.

  • Strong Python programming skills.

  • Demonstrated research experience with NLP, information extraction, LLMs, RAG, transformers, structured prediction, or scientific text mining.

  • Ability to design controlled computational experiments, create benchmark datasets, and analyze results rigorously.

  • Familiarity with biological, biomedical, or scientific data.

  • Strong written communication skills and interest in publishing methods-oriented research.

  • Comfort working with complex, evolving research codebases and interdisciplinary teams.

 

Preferred Qualifications

 

  • Experience with scientific document processing, PDF parsing, biomedical literature mining, or methods-section extraction.

  • Experience with knowledge graphs, ontologies, graph databases, graph algorithms, or semantic data modeling.

  • Hands-on experience with fine-tuning LLMs, LoRA/QLoRA, Hugging Face, PyTorch, or API-based model evaluation.

  • Hands-on experience with prompt engineering, structured JSON extraction, schema validation, tool use, or agentic LLM workflows.

  • Hands-on experience with RAG systems, vector search, graph-augmented retrieval, or natural-language query over structured data.

  • Exposure to bioinformatics concepts (e.g., sequence alignment, clustering, or phylogenetic analysis) that can inform protocol comparison and similarity methods.

  • Background in stem cell biology, organoids, developmental biology, wet-lab protocols, or biological assays, enabling more effective collaboration with domain experts.

 

Disclaimer: The above description is meant to illustrate the general nature of work and level of effort being performed by individuals assigned to this position or job description. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job description or responsibilities as needed.

The diversity of Axle’s employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment based on age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate.

Accessibility: If you need an accommodation as part of the employment process please contact: careers@axleinfo.com

This role has a market-competitive salary with an anticipated base compensation range listed below. Actual salaries will vary depending on a candidate’s experience, qualifications, skills, and location.

Salary Range
$90,000—$100,000 USD

Junior Illustrator

(ID: 2026-2264)

Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations nationally and abroad. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).

 

Benefits We Offer:

  • 100% Medical, Dental & Vision Coverage for Employees
  • Paid Time Off and Paid Holidays
  • 401K match up to 5%
  • Educational Benefits for Career Growth
  • Employee Referral Bonus
  • Flexible Spending Accounts:
    • Healthcare (FSA)
    • Parking Reimbursement Account (PRK)
    • Dependent Care Assistant Program (DCAP)
    • Transportation Reimbursement Account (TRN)

 

Position Summary

We are seeking a creative and detail-oriented Junior Illustrator to support NIH research programs through the development of high-quality visual communications in Hamilton, Montana. This role involves producing a wide range of visual materials—including illustrations, animations, video, web content, and graphic designs—that help communicate complex scientific concepts to diverse audiences. The ideal candidate will collaborate closely with subject matter experts and visual information specialists to transform scientific ideas into clear, engaging, and accessible visual products.
 

Key Responsibilities

  • Support NIH research programs by completing a variety of visualization projects as assigned.

  • Create illustrations, videos, animations, web content, and graphic designs for publication and presentation.

  • Ensure all published materials meet Section 508 compliance accessibility standards.

  • Collaborate with subject matter experts and visual information specialists to interpret broad scientific concepts and translate them into accurate, effective visual materials.

  • Assist with storyboarding, designing, developing, producing, and editing video and animations to help document and communicate scientific results.

  • Assist in the design, production, reproduction, and display of original visual products and materials.

  • Participate in program activities, including sharing projects, knowledge, and technical skills with team members and stakeholders.

 

Qualifications

  • Bachelor’s degree in Illustration, Graphic Design, Animation, Visual Communications, or a related field, or equivalent combination of education and experience.

  • Demonstrated ability to create visual content across multiple formats, including illustration, video, animation, and digital/web media.

  • Familiarity with design and multimedia production tools such as Adobe Creative Suite or similar software.

  • Basic understanding of 2-D and 3-D animation, video editing, and storyboarding.

  • Knowledge of or willingness to learn Section 508 compliance requirements for accessible publications.

  • Strong communication and collaboration skills, with the ability to work effectively with scientific and technical subject matter experts.

  • Ability to manage multiple assignments, meet deadlines, and maintain attention to detail.

 

Preferred Qualifications

  • Experience supporting scientific, medical, technical, or research-based communications.

  • Familiarity with visualizing complex scientific or technical information for varied audiences.

  • Interest in biomedical research and public health communications.

 

 

Disclaimer: The above description is meant to illustrate the general nature of work and level of effort being performed by individuals assigned to this position or job description. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job description or responsibilities as needed.

The diversity of Axle’s employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment based on age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate.

Accessibility: If you need an accommodation as part of the employment process please contact: careers@axleinfo.com

This role has a market-competitive salary with an anticipated base compensation range listed below. Actual salaries will vary depending on a candidate’s experience, qualifications, skills, and location.

Salary Range
$60,000—$70,000 USD

Genomics Technician

(ID: 2026-2186)

 

Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations nationally and abroad. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).

 

Benefits We Offer:

  • 100% Medical, Dental & Vision Coverage for Employees
  • Paid Time Off and Paid Holidays
  • 401K match up to 5%
  • Educational Benefits for Career Growth
  • Employee Referral Bonus
  • Flexible Spending Accounts:
    • Healthcare (FSA)
    • Parking Reimbursement Account (PRK)
    • Dependent Care Assistant Program (DCAP)
    • Transportation Reimbursement Account (TRN)

Axle is seeking a Genomics Technician to join our vibrant team at the National Institutes of Allergy and Infectious Diseases (NIAID) supporting the Center for Human Immunology, Autoimmunity, and Inflammation (CHI). CHI is a trans-NIH initiative whose mission is to provide a collaborative resource for NIH investigators. Created in 2009, CHI is focused on combining scientific expertise, advanced technologies and tailored informatics, to better understand human immune function and pathophysiology. Systems-scale approaches are developed and used for deep profiling of immune states during disease progression or clinical interventions, such as vaccination and cancer immunotherapy with an ultimate goal to provide novel immunological insights and enable key lab discoveries to be rapidly translated into disease prevention, diagnosis, and treatment.

 

Job Duties:

  • Member of high-performing interdisciplinary research team.

  • Process cell suspensions for single-cell analysis using 10x Genomics instruments.

  • Perform bulk RNA-Seq, scRNA-Seq, CITE-Seq, ATAC-Seq, and other immune profiling single-cell assays.

  • Prepare and QC RNA and DNA samples for sequencing.

  • Perform routine maintenance, operation and troubleshooting of 10x Genomics, Illumina, and high-throughput robotic automation instrumentation.

  • Perform spatial transcriptomics using 10x Visium or similar technologies.

  • Sample processing and Biobanking.

  • Keep detailed records of experimental procedures.

 

Qualifications:

  • Bachelor’s degree or higher in molecular biology, biochemistry, or related field.

  • Minimum of two (2) years of work experience preparing NGS and/or 10x libraries and performing Illumina sequencing.

  • Proficient in molecular and cellular biology techniques.

  • Familiarity with bioinformatics/sequence analysis is desirable but not required.

  • Experience with spatial transcriptomics technologies, specifically 10x Visium or VisiumHD, is required. 

 

Disclaimer: The above description is meant to illustrate the general nature of work and level of effort being performed by individuals assigned to this position or job description. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job description or responsibilities as needed.

The diversity of Axle’s employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment based on age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate.

Accessibility: If you need an accommodation as part of the employment process please contact: careers@axleinfo.com

This role has a market-competitive salary with an anticipated base compensation range listed below. Actual salaries will vary depending on a candidate’s experience, qualifications, skills, and location.

#INDPSD

Salary Range
$80,000—$90,000 USD

Bioinformatics/Data Scientist

(ID: 2025-0696)

Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations nationally and abroad. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).

 

Axle is seeking a Bioinformatics/Data Scientist to join our vibrant team at the National Institutes of Health (NIH) supporting the Standardized Organoid Model Center in Frederick, MD. The Standardized Organoid Model Center is an NIH-funded initiative dedicated to advancing organoid research through the development of validated, reproducible, and well-characterized organoid models. The center brings together interdisciplinary teams of researchers to establish standardized protocols, develop quality control measures, and create resources that will benefit the broader organoid research community.

 

Benefits We Offer:

  • 100% Medical, Dental & Vision Coverage for Employees
  • Paid Time Off and Paid Holidays
  • 401K match up to 5%
  • Educational Benefits for Career Growth
  • Employee Referral Bonus
  • Flexible Spending Accounts:
    • Healthcare (FSA)
    • Parking Reimbursement Account (PRK)
    • Dependent Care Assistant Program (DCAP)
    • Transportation Reimbursement Account (TRN)

 

Overview

The Bioinformatics/Data Scientist will conduct comprehensive analyses of multi-omics data generated from organoid systems and corresponding normal tissues. This position is central to the SOM Center’s research objectives, focusing on characterizing organoid fidelity, identifying biomarkers of successful differentiation, and developing computational frameworks for organoid quality assessment.

 

Responsibilities

  • The successful candidate will analyze complex datasets including single-cell RNA sequencing, bulk RNA sequencing, proteomics, and metabolomics data from various organoid systems and their tissue counterparts.
  • The position will develop and implement computational pipelines for data processing, quality control, and statistical analysis.
  • A major component of the role involves integrating SOM-generated data with publicly available datasets to benchmark organoid characteristics against normal tissue profiles.
  • The position requires close collaboration with experimental teams to interpret results and guide protocol optimization, as well as contributing to manuscript preparation and presenting findings at scientific conferences.

 

Required Qualifications

  • Candidates must hold a PhD in bioinformatics, computational biology, biostatistics, or a related quantitative field.
  • Extensive experience with single-cell data analysis, including familiarity with tools such as Seurat, Scanpy, or similar platforms, is essential.
  • Strong programming skills in R and Python are required, along with experience in statistical analysis and data visualization.
  • Knowledge of proteomics and metabolomics data analysis workflows is necessary.

 

Preferred Qualifications

  • Previous experience analyzing organoid datasets is strongly preferred.
  • Experience with machine learning approaches for biological data, familiarity with pathway analysis tools, and knowledge of developmental biology principles will be considered valuable assets.
  • Experience with high-performance computing environments and version control systems is desirable.

 

Disclaimer: The above description is meant to illustrate the general nature of work and level of effort being performed by individuals assigned to this position or job description. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job description or responsibilities as needed.

The diversity of Axle’s employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment based on age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate.

Accessibility: If you need an accommodation as part of the employment process please contact: careers@axleinfo.com

This role has a market-competitive salary with an anticipated base compensation range listed below. Actual salaries will vary depending on a candidate’s experience, qualifications, skills, and location.

#INDPSD

Salary Range
$105,000—$120,000 USD

Bioinformatics Scientist

(ID: 2026-1976)
 
Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations nationally and abroad. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).

Benefits We Offer:

  • 100% Medical, Dental & Vision Coverage for Employees
  • Paid Time Off and Paid Holidays
  • 401K match up to 5%
  • Educational Benefits for Career Growth
  • Employee Referral Bonus
  • Flexible Spending Accounts:
    • Healthcare (FSA)
    • Parking Reimbursement Account (PRK)
    • Dependent Care Assistant Program (DCAP)
    • Transportation Reimbursement Account (TRN)

Axle is seeking a highly ambitious, adaptable, structured, and detail-oriented Bioinformatics Scientist to join our vibrant team at the National Institutes of Health (NIH), National Institute of Allergy and Infectious Diseases (NIAID), Division of Intramural Research (DIR), Research Technologies Branch (RTB), Integrated Data Sciences Section (IDSS) in Bethesda, MD. 

 
Responsibilities:

  • Address bioinformatics, scientific computing, and data analysis needs of users within the Division of Intramural Research (DIR) at NIAID and their collaborators by lending expertise in the proper statistical design of biological experiments involving high-throughput genome-scale technologies, data mining and knowledge discovery techniques, automated workflow development, statistical and scientific experimental design consulting.
  • Provide bioinformatics support to include somatic and germline variant calling and analysis, single-cell and bulk gene expression analysis, de novo assembly of genomes and transcriptomes, comparative genomics of model and non-model organisms, proteomics, ChIP-seq, ATAC-seq, and the development of high-throughput pipelines for the analysis of the above data modalities.
  • Provide programming and troubleshooting support to the Research Technologies Branch (RTB) of the National Institute of Allergy and Infectious Diseases (NIAID) and collaborating Institutes in the dissemination of research data.
  • Perform computational data analysis on genomic and clinical research data.
  • Work with staff on scientific programming and experimental design. Provide statistical support/analysis on research data.
  • Contribute to and co-author scientific publications in leading peer-reviewed journals.
  • Contribute to the development of a scalable and flexible resource to provide NGS bioinformatics, structural biological and computational, machine learning data support to NIAID scientists and investigators.
  • It is expected that the bioinformatics scientist will need strong skills in the following:
    • NGS analysis (whole-exome, whole-genome, RNA-seq, ChIP-Seq, both long- and short-read technologies, etc.)
    • Statistical modeling
    • Scripting
    • Biological interpretation

Specific Qualifications:

  • Ability to obtain and maintain a Public Trust Security clearance
  • Minimum Bachelor’s degree in related field, Master’s or Ph.D. preferred
  • 4+ years of experience in bioinformatics
  • 2+ years of experience developing and maintaining production bioinformatics pipelines
  • Expert in two (2) of the following languages: Python, R, C/C++, sh/bash
  • Experience building images using one (1) of the following: Docker, Podman, Singularity/Apptainer
  • Expert in one (1) pipeline framework: Snakemake, Nextflow, CWL/WDL
  • Expertise building technical and user documentation for tools, pipelines, and applications
  • Experience building pipelines locally on-premise using available HPC infrastructure
  • Experience building pipelines/applications in the Cloud with AWS/GCP/Azure is a plus
  • Experience building applications using one (1) of the following frameworks is a plus: Django, Flask, RShiny, Electron, Flutter, React
  • Experience working in a laboratory setting is a plus but not required

 

Disclaimer: The above description is meant to illustrate the general nature of work and level of effort being performed by individuals assigned to this position or job description. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job description or responsibilities as needed.

The diversity of Axle’s employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment based on age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate.

Accessibility: If you need an accommodation as part of the employment process please contact: careers@axleinfo.com

This role has a market-competitive salary with an anticipated base compensation range listed below. Actual salaries will vary depending on a candidate’s experience, qualifications, skills, and location.

Salary Range
$120,000—$130,000 USD

Electron Microscopy Specialist

(ID: 2026-1867)

 

Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations nationally and abroad. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).

 

Benefits We Offer:

  • 100% Medical, Dental & Vision Coverage for Employees
  • Paid Time Off and Paid Holidays
  • 401K match up to 5%
  • Educational Benefits for Career Growth
  • Employee Referral Bonus
  • Flexible Spending Accounts:
    • Healthcare (FSA)
    • Parking Reimbursement Account (PRK)
    • Dependent Care Assistant Program (DCAP)
    • Transportation Reimbursement Account (TRN)

 

 

About the Role

Axle is looking for an experienced Electron Microscopy Specialist to join our team supporting research at NIAID’s Rocky Mountain Laboratories in Hamilton, Montana. In this role, you’ll work closely with scientists in a collaborative, fast-paced environment, helping generate high-quality imaging data that supports infectious disease research.

 

This is a hands-on position for someone who enjoys both the technical side of electron microscopy and the collaborative nature of working with different research groups. If you have strong immuno-EM experience and are excited about learning and applying newer approaches like CLEM, FIB-SEM, and cryo-EM, this could be a great fit.

 

What You’ll Do

  • Prepare biological samples for electron microscopy (fixation, embedding, sectioning, staining) and perform imaging and analysis.

  • Design and conduct immuno-electron microscopy (immuno-EM) experiments.

  • Operate and help maintain TEM and/or SEM instruments, including troubleshooting when needed.

  • Work closely with NIAID investigators to plan experiments, interpret results, and solve technical challenges.

  • Help bring new capabilities online, including techniques like CLEM, FIB-SEM, and cryo-EM.

  • Keep clear, well-organized records in line with NIH standards for rigor and reproducibility.

  • Train and support other lab members or facility users in EM techniques.

  • Contribute to the overall operation of the lab, including equipment upkeep and safety compliance.

 

What We’re Looking For

  • Degree in a relevant field (Cell Biology, Structural Biology, Biophysics, or similar).

  • At least 5 years of relevant job experience in biological electron microscopy.

  • Solid understanding of EM sample preparation and imaging workflows.

  • Strong experience with immuno-electron microscopy.

  • Experience operating and troubleshooting EM instruments.

  • Someone who communicates well, works collaboratively, and is comfortable supporting multiple projects.

 

Nice to Have

  • Experience working in a shared resource or core facility.

  • Experience with, or strong interest in learning:

  • Correlative Light and Electron Microscopy (CLEM)

  • Focused Ion Beam-SEM (FIB-SEM)

  • Cryo-electron microscopy (cryo-EM)

  • Familiarity with image analysis tools.

 

What Makes Someone Successful in This Role

  • You’re a team player who enjoys working with a range of scientists and projects.

  • You’re curious and motivated to learn new techniques and technologies.

  • You’re organized, detail-oriented, and take pride in producing high-quality data.

  • You can balance multiple priorities without losing track of the details.

 

 

Disclaimer: The above description is meant to illustrate the general nature of work and level of effort being performed by individuals assigned to this position or job description. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job description or responsibilities as needed.

The diversity of Axle’s employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment based on age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate.

Accessibility: If you need an accommodation as part of the employment process please contact: careers@axleinfo.com

This role has a market-competitive salary with an anticipated base compensation range listed below. Actual salaries will vary depending on a candidate’s experience, qualifications, skills, and location.

#IND

Salary Range
$70,000—$80,000 USD

AI/ML Scientist/Developer

(ID: 2025-0402)

Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations nationally and abroad. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).

 

Axle is seeking a AI/ML Scientist/Developer to join our vibrant team at the National Institutes of Health (NIH) supporting the Standardized Organoid Model Center in Frederick, MD. The Standardized Organoid Model Center is an NIH-funded initiative dedicated to advancing organoid research through the development of validated, reproducible, and well-characterized organoid models. The center brings together interdisciplinary teams of researchers to establish standardized protocols, develop quality control measures, and create resources that will benefit the broader organoid research community.

 

Benefits We Offer:

  • 100% Medical, Dental & Vision Coverage for Employees
  • Paid Time Off and Paid Holidays
  • 401K match up to 5%
  • Educational Benefits for Career Growth
  • Employee Referral Bonus
  • Flexible Spending Accounts:
    • Healthcare (FSA)
    • Parking Reimbursement Account (PRK)
    • Dependent Care Assistant Program (DCAP)
    • Transportation Reimbursement Account (TRN)

 

Overview

The AI/ML Scientist/Developer will develop innovative computational models to predict and optimize organoid growth and differentiation protocols. This position represents a unique opportunity to apply cutting-edge machine learning techniques to advance organoid standardization and contribute to the development of predictive models for tissue engineering applications.

 

Responsibilities

  • The successful candidate will design and implement machine learning models that predict organoid development outcomes based on protocol parameters, environmental conditions, and molecular characterization data.
  • They will develop in silico models that can simulate organoid growth dynamics and identify optimal conditions for reproducible organoid generation.
  • The role involves creating feedback loops between experimental validation and computational prediction to iteratively improve protocol standardization.
  • Collaboration with experimental teams to design validation experiments and with data scientists to integrate multi-modal datasets will be essential components of this position.

 

Required Qualifications

  • Candidates must possess a Master’s degree or PhD in computer science, engineering, applied mathematics, or a related field with demonstrated experience in AI/ML model development.
  • Strong programming skills in Python, R, or similar languages are required, along with experience with machine learning frameworks such as TensorFlow, PyTorch, or scikit-learn.
  • Previous experience applying computational methods in biological laboratory settings is necessary, with knowledge of experimental design principles and biological data types.

 

Preferred Qualifications

  • Experience with organoid systems or tissue engineering applications is highly desirable.
  • Knowledge of differential equations, systems biology modeling, and experience with deep learning approaches for biological applications will be considered strong assets.
  • Familiarity with cloud computing platforms and containerization technologies is preferred.

Disclaimer: The above description is meant to illustrate the general nature of work and level of effort being performed by individuals assigned to this position or job description. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job description or responsibilities as needed.

The diversity of Axle’s employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment based on age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate.

Accessibility: If you need an accommodation as part of the employment process please contact: careers@axleinfo.com

This role has a market-competitive salary with an anticipated base compensation range listed below. Actual salaries will vary depending on a candidate’s experience, qualifications, skills, and location.

 

Salary Range
$115,000—$130,000 USD